Plants have an immune system that resists infection, yet 10% of the world's agricultural production is lost annually to diseases caused by bacteria, fungi, and viruses. Understanding how disease resistance works may help combat this scourge.
In a new study published online this week in the open-access journal PLoS Biology, Tessa Burch-Smith, Savithramma Dinesh-Kumar, and colleagues show how one aspect of the plant immune system is defined by the gene-for-gene hypothesis: a plant Resistance (R) gene encodes a protein that specifically recognizes and protects against one pathogen or strain of a pathogen carrying a corresponding Avirulence (Avr) gene.
In tobacco and its relatives, the N resistance protein confers resistance to infection by the Tobacco mosaic virus (TMV).