How do you get information from a preparation that is transparent? How can you still see a three-dimensional image through a microscope? Dutch researcher Rajesh S. Pillai investigated a new way of illuminating preparations under the microscope. For example, he could investigate the microstructure of food, which is important for the taste and shelf-life. Furthermore, this technique is highly promising for research into how fat is stored in the human body.

A blow with the hammer

Images can only be made under the microscope if the preparation is illuminated. Sometimes using a single lamp is not enough, for example when a three-dimensional image of a transparent sample is needed. In this project Pillai used a laser that emitted extremely short pulses of infrared light.

The rise of multicellular animals about 540 million years ago was a turning point in the history of life. A group of Finnish scientists suggests a new climate-biosphere interaction mechanism for the underlying processes in a new study, which will be published on February 14, 2007 in PLoS ONE, the international, peer-reviewed, open-access, online publication from the Public Library of Science (PLoS).

The theory invokes cold, ice-containing climates as a key precursor for multicellular life. If the model turns out to be correct, one can assume that complex life might exist also around stars which are more massive and short-lived than the Sun.

New research findings now appearing online in the Journal of Experimental Social Psychology began with a professor's desire to understand why her husband often seemed to ignore her requests for help around the house.

"My husband, while very charming in many ways, has an annoying tendency of doing exactly the opposite of what I would like him to do in many situations," said Tanya L. Chartrand, an associate professor of marketing and psychology at Duke University's Fuqua School of Business.

When Chartrand envisioned a formal academic study of people's resistance to the wishes of their partners, parents or bosses, her husband, Gavan Fitzsimons, became not only her inspiration, but also her collaborator.

The far-reaching influence of Spanish and Portuguese colonisers appears not to have extended to South American agriculture, scientists studying a 1,400-year-old Andean mummy have found.

The University of Manchester researchers compared the DNA of ancient maize found in the funerary offerings of the mummy and at other sites in northwest Argentina with that grown in the same region today.

Surprisingly, they found both ancient and modern samples of the crop were genetically almost identical indicating that modern European influence has not been as great as previously thought.


Photograph of the mummy and a close-up of the maize. (Credit: Dr Verónica Lia, Universidad de Buenos Aires)

Scientists using data from the HRSC experiment onboard ESA's Mars Express spacecraft have produced the first 'hiker's maps' of Mars. Giving detailed height contours and names of geological features in the Iani Chaos region, the maps could become a standard reference for future Martian research. The maps are known as topographic maps because they use contour lines to show the heights of the landscape.


This image of Mars taken by the High Resolution Stereo Camera on board ESA's Mars Express outlines the scales (1:200 000, 1:100 000 and 1:50 000) of the series of topographic maps of the planet's surface that can be realized thanks to HRSC data.

In work that could dramatically boost the capabilities of "lab on a chip" devices, MIT researchers have created a way to use tiny bubbles to mimic the capabilities of a computer.

The team, based at MIT's Center for Bits and Atoms, reports that the bubbles in their microfluidic device can carry on-chip process control information, just like the electronic circuits of a traditional microprocessor, while also performing chemical reactions. The work will appear in the Feb. 9 issue of Science.


MIT researchers have developed a computer chip that runs on microbubbles like these. (Photo courtesy of Manu Prakash)

Although no two brains are alike, they can display a comparable pattern of neural activity when exposed to similar sensory input. Scientists at the Max Planck Institute for Dynamics and Self-Organization in Göttingen have now developed a mathematical method to design networks from neural cells which exhibit a predefined pattern dynamics. The researchers hope that their method will assist them in getting closer to understanding which of the possible network configurations was privileged by evolution -- and why (Physica D: Nonlinear Phenomena, December, 2006).


Different neuronal networks can bear the same pattern of activity -- as shown in this example of a network made of 16 neurons.

For cells that hold so much promise, stem cells' potential has so far gone largely untapped. But new research from Rockefeller University and Howard Hughes Medical Institute scientists now shows that adult stem cells taken from skin can be used to clone mice using a procedure called nuclear transfer. The findings are reported in the Feb. 12 online edition of the Proceedings of the National Academy of Sciences.


Using a technique called nuclear transfer, mice were cloned using adult skin stem cells (right) and a more differentiated type of skin cell (left). The mouse on the right is almost two years old and the mouse on the right is one and a half.

The Scripps Research team, led by neuroscientists Manuel Sanchez-Alavez and Tamas Bartfai, discovered that mice genetically altered to lack a molecule known as the EP3 receptor tend to be more active during their normal sleep cycle and to eat more. In the study, this led to weight increases of up to 30 percent relative to mice with the receptors.

The EP3 receptor is one of four types of receptors for prostaglandin E2 (PGE2), the most important inflammatory mediator that controls a variety of physiological functions including fever, fertility, and blood pressure.

Some breaking news, just in time for Valentine's Day: Researchers have identified something called "sperm competition" that they think has evolved to ensure a genetic future. In sexual reproduction, natural selection is generally thought of as something that happens prior to – and in fact leads to -- the Big Event. This thinking holds, for example, that we are drawn to physical features that tell us our partner is healthy and will give us a fighting chance to carry on our genetic lineage.