Between the January 1589 and the spring of 1590, at Helmstedt, Giordano Bruno wrote "The Lulliana Medicine”. This work consists of a practical application of the Lullian System in the medical astrology. The text incorporate large sections of Explanatio Compendiosaque Applicatio Artis Illuminati Doctoris Magistri Raymundi Lulli (1235-1315), edited by the Franciscan Bernard de Lavinheta (c.1517). The work opens with the premise that health is determined by the balance of four elements, fire hot and dry, the air hot and humid, the water cold and wet and the earth dry and warm. Regarding the astrological studies applied to the medical art, Bruno gave to the world a vision of nature alive full of magic and spirituality.

Abu Ali al-Hussein Ibn Sina famous with the name of Avicenna, was born in Persia in the 
980 at Qishlak Afshona, near Bukhara, Uzbekistan. By the age of eighteen years, possessor of an 
immensest philosophical-scientific culture, undertakes the doctor profession. Avicenna was 
studious of Hippocrates and Galen therefore developed the theory of four humors and the 
derived complexions. Avicenna is also known to fuse philosophy and medicine all in one. 
Follower of Aristotle and Plato, its infuence on the western medicine was enormous, 
especially through a work that became soon one of the medicine books more used in the 

Hypomelanosis conditions are known since ancient times. The most ancient names to describe these pictures were "Shwetakustha" and "Suitra".

Hildegard von Bingen (1098-1179) was a remarkable woman. At a time when few women wrote, Hildegard, known as "Sybil of the Rhine", produced major works of theology, medicine and visionary writings. Hildegard composed music and spoke of Christ as God's song.  

At Cairo museum, on Queen Hatshepsut’s tomb in Deir el Bahari,it shows the chief Parihou with his wife Ati, Queen of Punt, (an area not still geographically established: Yemen, Somalia, Ethiopia, Eritrea, Sudan?) while they offer gifts to the Egyptian Queen Hatshepsut (1516-1481 BC).

A naval expedition to the mysterious land of Punt was undertaken in the summer of Hatshepsut’s eighth year as queen; she sent a fleet of five ships, headed by her Chancellor Senenmet. The Queen of Punt shows a rugged face, gluteal and femoral obesity, hyperlordosis and symmetrical deposits of fat on the trunk, limbs and thighs.