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What Next For Messenger RNA (mRNA)? Maybe Inhalable Vaccines

No one likes getting a needle but most want a vaccine. A new paper shows progress for messenger...

Toward A Single Dose Smallpox And Mpox Vaccine With No Side Effects

Attorney Robert F. Kennedy Jr. and his US followers over the last 25 years have staunchly opposed...

ChatGPT Is Cheaper In Medicine And Does Better Diagnoses Even Than Doctors Using ChatGPT

General medicine, routine visits and such, have gradually gone from M.D.s to including Osteopaths...

Even After Getting Cancer, Quitting Cigarettes Leads To Greater Longevity

Cigarettes are the top lifestyle risk factor for getting cancer, though alcohol and obesity have...

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For the first time gene therapy for cystic fibrosis has shown a significant benefit in lung function compared with placebo, in a phase 2 randomized trial. The technique replaces the defective gene response for cystic fibrosis by using inhaled molecules of DNA to deliver a normal working copy of the gene to lung cells.

“Patients who received the gene therapy showed a significant, if modest, benefit in tests of lung function compared with the placebo group and there were no safety concerns,” said senior author Professor Eric Alton from the National Heart and Lung Institute at Imperial College London. “Whilst the effect was inconsistent, with some patients responding better than others, the results are encouraging.”

Every time you put on bug spray this summer, you're another front in the ongoing war between humans and mosquitoes - and being a citizen scientist in a complex evolutionary experiment.

Scientists have found that between 5 and 20 percent of a mosquito population's genome is subject to evolutionary pressures at any given time, creating a strong signature of local adaptation to environment and humans. This means that individual populations are likely to have evolved resistance to whatever local selection pressures are typical in their area, and that understanding the genomes of those populations could one day help inform agencies about which pesticides are likely to be most effective against them.

The 2014-2015 flu vaccine didn't work as well compared to previous years because the H3N2 virus recently acquired a mutation that concealed the infection from the immune system. A study published on June 25 in Cell Reports reveals the major viral mutation responsible for the mismatch between the vaccine strain and circulating strains. The research will help guide the selection of viral strains for future seasonal flu vaccines.

Too much male sexual attention harms attractive females, according to a new Australian and Canadian study on fruit flies.

Associate Professor Steve Chenoweth from The University of Queensland's School of Biological Sciences said the study showed that male harassment of females hampered the species' ability to adapt to new environmental conditions.

"We found that sexually attractive females were overwhelmed by male suitors," he said.

"Female fruit flies with superior genes that allow them to lay more eggs were so attractive to male suitors they spent most of the time fending off male suitors rather than actually laying eggs. The end result was that these supposedly 'superior' genes could not be passed on to the next generation."

The Supreme Court seems poised to take on the abortion issue again, and with reason.

On June 29, by a five-to-four vote, the Court temporarily blocked a Texas law that would force many clinics to close, guaranteeing that the state’s new law would not take effect until the justices decide whether to rule on its constitutionality. And just today, June 30, the Court did not take action on a case involving a similar abortion restriction passed in Mississippi.

The first species of Yeti Crab from hydrothermal vent systems of the East Scotia Ridge in the Southern Ocean, Antarctica, has been described in a study by Sven Thatje from University of Southampton, and colleagues.

The species of Yeti crab Kiwa tyleri belongs to an enigmatic group of squat lobsters, known as Kiwaidae, that thrive in the hot waters surrounding the geothermally heated hydrothermal vents. It is the dominant species at these sites, occurring at extremely high densities exceeding 700 specimens per square meter.