The emerging picture of microbes as gene-swapping collectives demands a revision of such concepts as organism, species and evolution itself.

One of the most fundamental patterns of scientific discovery is the revolution in thought that accompanies a new body of data. Satellite-based astronomy has, during the past decade, overthrown our most cherished ideas of cosmology, especially those relating to the size, dynamics and composition of the Universe.

Similarly, the convergence of fresh theoretical ideas in evolution and the coming avalanche of genomic data will profoundly alter our understanding of the biosphere — and is likely to lead to revision of concepts such as species, organism and evolution.

As you probably know ulcerative colitis affects around  half a million Americans.

Howard Hughes Medical Institute researchers have developed two strategies to reactivate the p53 gene in mice, causing blood, bone and liver tumors to self destruct. The p53 protein is called the "guardian of the genome" because it triggers the suicide of cells with damaged DNA.

Inactivation of p53 can set the stage for the development of different types of cancer. The researchers' findings show for the first time that inactivating the p53 gene is necessary for maintaining tumors. While the researchers caution that cancers can mutate to circumvent p53 reactivation, they believe their findings offer ideas for new approaches to cancer therapy.

A new survey by researchers at Oregon State University and the U.S. Environmental Protection Agency of more than 600 rivers and streams in the western United States found widespread mercury concentrations in fish.

Though few of the more than 2,700 fish analyzed in the study contained alarmingly high levels of mercury, the prevalence of the element throughout 12 western states caught the researchers somewhat by surprise.

In a new study from The American Journal of Human Genetics, a research team lead by Xinzhi Zhao and Ruqi Tang (Shanghai Jiao Tong University) present evidence that genetic variation may indicate predisposition to schizophrenia.

Nobody questions that the color of our eyes is encoded in our genes. When it comes to behavior the concept of "DNA as fate" quickly breaks down -- it's been long accepted that both genes and the environment shape human behavior. But just how much sway the environment holds over our genetic destiny has been difficult to untangle.

Scientists at the Salk Institute for Biological Studies have found a clever way to sort one from the other: They compared the social behavior of children with Williams syndrome -- known for their innate drive to interact with people -- across cultures with differing social mores. Their study, published in a forthcoming issue of Developmental Science, demonstrates the extent of culture's stamp on social behavior.

A team of UCLA and California Institute of Technology chemists reports in the Jan. 25 issue of the journal Nature the successful demonstration of a large-scale, "ultra-dense" memory device that stores information using reconfigurable molecular switches. This research represents an important step toward the creation of molecular computers that are much smaller and could be more powerful than today's silicon-based computers.

The 160-kilobit memory device uses interlocked molecules manufactured in the UCLA laboratory of J.

The Ikerlan-IK4 and Gaiker-IK4 Technological Centre have patented a device which is capable of the rapid and effective diagnosis of infectious diseases caused by various bacteria, notable amongst which are Salmonella, Campylobacter and Listeria, the causal agents of most gastroenteritis cases due to food poisoning, as well as of other symptomatologies associated with this condition.

Smokers with a damaged insula -- a region in the brain linked to emotion and feelings -- quit smoking easily and immediately, according to a study in the Jan. 26 issue of the journal Science.

The study provides direct evidence of smoking's grip on the brain.

A team led by biochemists at the University of California, San Diego has found what could be a long-elusive mechanism through which inflammation can promote cancer. The findings may provide a new approach for developing cancer therapies.

The study, published in the January 26 issue of the journal Cell, shows that what scientists thought were two distinct processes in cells—the cells’ normal development and the cells’ response to dangers such as invading organisms—are actually linked.