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The Fingerprints Of God

I found the premise of Barbara Bradley Hagerty's new book "Fingerprints of God" quite intriguing...

Crowds, Solubility And The Future Of Organic Chemistry

This week I participated in a Social Media Day at NIST. During my talk I provided an overview of...

Crowds, Solubility And The Future Of Organic Chemistry

This week I participated in a Social Media Day at NIST. During my talk I provided an overview of...

Are There Facts In Experimental Sciences?

I recently attended an NSF workshop on eChemistry: New Models for Scholarly Communication in Chemistry...

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Jean-Claude BradleyRSS Feed of this column.

Jean-Claude Bradley is an Associate Professor of Chemistry and the E-Learning Coordinator for the College of Arts and Sciences at Drexel University in Philadelphia, PA.

He teaches organic

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Crowdsourcing Drug Development

Crowdsourcing Drug Development

Jan 16 2008 | comment(s)

Yesterday I had the privilege of attending a workshop at the NIH on the National Cancer Institute Clinical Development of Small Molecules:
This one-day workshop will provide specialized training and information to NCI-supported investigators who plan to undertake clinical development of novel concepts and who are directly involved with implementing translational clinical research.
Scientific American Article On Science 2.0

Scientific American Article On Science 2.0

Jan 09 2008 | comment(s)

Mitch Waldrop has written an informative piece on the Science 2.0 movement in Scientific American:



Science 2.0: Great New Tool, or Great Risk?



Consistent with the content of the article, Mitch invites feedback:

Welcome to a Scientific American experiment in "networked journalism," in which readers—you—get to collaborate with the author to give a story its final form.


The Value Of Chemistry Results

The Value Of Chemistry Results

Jan 03 2008 | comment(s)

Chemical research has traditionally been organized in either experiment-centric or molecule-centric models. This makes sense from the chemist's standpoint. When we think about doing chemistry, we conceptualize experiments as the fundamental unit of progress. This is reflected in the laboratory notebook, where each page is an experiment, with an objective, a procedure, the results, their analysis and a final conclusion optimally directly answering the stated objective. When we think about searching for chemistry, we generally imagine molecules and transformations.
Subcellular Drug Transport Now Open Notebook Science

Subcellular Drug Transport Now Open Notebook Science

Dec 25 2007 | comment(s)

I recently reported on a new collaborator who agreed to work with us in the open on modelling subcellular drug transport. I am very pleased to report that Gus Rosania has now created an entire wiki (1CellPK) for his lab to use as an open notebook.
More Open Collaboration For Drug Design

More Open Collaboration For Drug Design

Dec 18 2007 | comment(s)

Rajarshi Guha has yet again made a key contribution to our UsefulChem project by connecting us with Gus Rosania at the University of Michigan. Gus is interested in a fully open collaboration to help us further prioritize our drug targets based on predicted subcellular drug transport:
It is the first time I hear about Open Notebook Science, but it sounds like a fantastic idea! My research group studies the subcellular transport of small molecules.
Camphor In Second Life

Camphor In Second Life

Dec 17 2007 | comment(s)

This term, the students in my organic chemistry class were presented with an opportunity to do an extra credit assignment using Second Life to represent concepts they learned in the course. When I was an undergraduate, finding molecules in articles was mainly done using the Chemical Abstracts books. A convenient way to find a specific molecule would be to look up the molecular formula and find the corresponding IUPAC name. Theoretically, one could figure out the IUPAC name from scratch but this can be very tricky for complex molecules and prone to error.