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... might alter weight regulation, the hormone most studied is leptin, a chemical that is made primarily in adipose tissue. Leptin is generally considered to be a "stop eating" signal to the brain. The ...

Blog Post - Ignatius Brady - Oct 22 2015 - 8:48pm - 0 attachments

... had mutations in MC4R, a gene known to be regulated by leptin (an appetite-suppressing hormone) and insulin in the human brain. ...

Article - News Staff - Jul 14 2015 - 8:00am - 0 attachments

... the action of an appetite-suppressing hormone called leptin. The findings are an early indicator that Celastrol could be developed ... amount of effort to treat obesity by breaking down leptin resistance, but these efforts have failed," says senior study author ...

Article - News Staff - May 27 2015 - 11:09am - 0 attachments

... to our bodies during the dark. Levels of the hormone leptin, which helps control hunger, go up. High levels of leptin mean we do not feel hungry while low levels make us hungry. Why does ...

Article - The Conversation - Apr 6 2015 - 9:00pm - 0 attachments

... body weight, in response to influences from the hormone leptin," says Low, a professor in the Department of Molecular and Integrative ... other transcription factors, and to examine the roles of leptin and estrogen in stimulating POMC cells. They also hope to use neurons ...

Article - News Staff - Apr 2 2015 - 1:35pm - 0 attachments

... in the body's appetite-controlling hormones, ghrelin and leptin. In a vicious cycle, the hormonal imbalance increases appetite, leading ...

Article - News Staff - Mar 17 2015 - 6:46pm - 0 attachments

... test their method, the researchers attached Herceptin® to leptin, a hormone that regulates body weight. They showed that the antibody-leptin molecule was just as effective in mice as natural leptin--and it didn't ...

Article - News Staff - Feb 9 2015 - 10:14pm - 0 attachments

... that were genetically engineered to be obese and lacking leptin, the hormone that signals mammals when they've eaten enough food. ...

Article - News Staff - Dec 10 2014 - 1:30pm - 0 attachments

... neurons. Green POMC neurons were activated by leptin (red nuclei). Credit: Yale University “These animals ate fat ...

Article - News Staff - Aug 2 2014 - 10:30am - 0 attachments

... from the relevant authorities, the authors note. Leptin — a hormone made by fat cells to regulate the amount of fat stored in ... reproduction and lactation." Since the discovery of Leptin, adipose tissue has been shown to play a key role in reproduction, ...

Article - News Staff - Jul 5 2014 - 10:30am - 0 attachments