Clinical Research

How To Identify The Birth Of New Cardiac Cells

New cells develop in the heart but how these cardiac cells are born and how frequently they are generated remains unclear. New research from Brigham and Women's Hospital used a novel method to identify these new heart cells and describe their origins ...

Article - News Staff - Dec 10 2012 - 4:32am

Are Clinical Trials Biased By Industry Sponsorship?

Clinical trials are obviously important.  The results influence what drugs are approved by regulatory bodies, which can have a billion-dollar impact on companies. Clinical trials have always been sponsored by industry- there has never been a meaningful  g ...

Article - News Staff - Dec 12 2012 - 5:30am

RS13702- Gene Variant Regulates Triglyceride Levels, Carriers Less Likely To Develop Heart Disease

Scientists have discovered a new gene mechanism that appears to regulate triglyceride levels and may protect carriers of a gene variant against cardiovascular disease, especially among those with greater intakes of polyunsaturated fat (PUFA).   ...

Article - News Staff - Dec 15 2012 - 5:26pm

Insulin Plus Betacellulin Inhibitor Limits Diabetes-Related Vision Damage In Mice

By combining insulin and an inhibitor of the epidermal growth factor (EGF) betacellulin,  Cleveland Clinic researcher Bela Anand-Apte, MD, PhD was able to halt the progression of diabetic macular edema (DME), according to data preseneted at the American S ...

Article - News Staff - Dec 24 2012 - 11:33am

BOVIGAM IFN-Gamma Tuberculosis Test Gets Positive Assessment In Europe

The European Food Safety Authority (EFSA) has reviewed field performance data of the BOVIGAM(R)Interferon-gamma (IFN-gamma) test and recommended such tests for inclusion in the official list of stand-alone tests for bovine tuberculosis (TB). BOVIGAM is cu ...

Article - News Staff - Dec 27 2012 - 12:00pm

Type 1 Diabetes Cured In Dogs

Researchers from the Universitat Autònoma de Barcelona report they can cure diabetes in large animals with a single session of gene therapy. Writing in Diabetes, they said the dogs recovered their health and no longer show symptoms of the disease. In some ...

Article - News Staff - Feb 9 2013 - 1:35pm

Coming: More Organs Grown From A Patient's Own Adult Stem Cells

Surgeon Paolo Macchiarini,  Professor of Regenerative Surgery at Karolinska Institutet, has become famous worldwide due to successfully transplanting bioengineered stem cell-based trachea, composed of both artificial and biological material, in patients. ...

Article - News Staff - Feb 18 2013 - 11:40am

Microbubbles And Ultrasound Improve Myocardial Remodelling After Infarction

Every year in Germany, approximately 280,000 people suffer a myocardial infarction; more than 52,000 die as a result. Due to an occluded vessel, parts of the heart muscle no longer have sufficient circulation and the tissue dies off. These regions are not ...

Article - News Staff - Feb 23 2013 - 4:30am

Bariatric Surgery Restores Pancreatic Function In Diabetes Patients

In a two-year sub-study of the STAMPEDE (Surgical Therapy And Medications Potentially Eradicate Diabetes Efficiently) trial, researchers  evaluated the effects of bariatric surgery and intensive medical therapy on blood sugar levels, body composition, and ...

Article - News Staff - Feb 26 2013 - 10:31am

SMIM1 Blood Protein Solves 61-Year-Old Vel Group Riddle

Discovery of a new protein that controls the presence of the Vel blood group antigen on our red blood cells will make it possible to use simple DNA testing to find blood donors for patients who lack the Vel antigen and need a blood transfusion, say resear ...

Article - News Staff - Apr 8 2013 - 3:22pm