Patients with Werner Syndrome show early signs of aging, including grey hair and wrinkled skin. They live on average about 45 years. It affects around 1 in 200,000 people in the U.S. but in Japan it is 1 in 40,000.
Why the difference? That is a mystery, like much of the disease. Since the underlying mechanisms are unknown there is no real treatment or cure, but
a new study found that in banana flies and
C. elegans worms with the equivalent of the syndrome that the dietary supplement nicotinamide adenine dinucleotide (NAD+) prolonged life and reduced age-related diseases like cancer.