Researchers at Harvard University and Princeton University have made a crucial step toward building biological computers, tiny implantable devices that can monitor the activities and characteristics of human cells. The information provided by these "molecular doctors," constructed entirely of DNA, RNA, and proteins, could eventually revolutionize medicine by directing therapies only to diseased cells or tissues.

Tissue engineering and regenerative medicine offer future patients greater options for treatment and cure of a wide array of urologic conditions, and controversies surrounding the sources of stem cells as well as their use have fueled increased research.

Here are highlights from the latest research:

ISOLATION OF HUMAN SPERMATOGONIAL STEM CELLS FROM TESTICULAR PARENCHYMA AND DIFFERENTIATION TOWARDS DIFFERENT TISSUES OF THE THREE HUMAN GERM LAYERS

The world's oldest wooden anchor was discovered during excavations in the Turkish port city of Urla, the ancient site of Liman Tepe -- the Greek 1st Millennium BCE colony of Klazomenai, by researchers from the Leon Recanati Institute for Maritime Studies of the University of Haifa. The anchor, from the end of the 7th century BC, was found near a submerged construction, imbedded approximately.1.5 meters underground.

An outbreak of drug-resistant wound infections among soldiers in Iraq likely came from the hospitals where they were treated, not the battlefield, according to a new study in the June 15 issue of Clinical Infectious Diseases, currently available online.

The outbreak of drug-resistant Acinetobacter baumannii-calcoaceticus complex (ABC) infections among U.S. service members injured in Iraq has been of major concern to military health care workers since it was first detected in 2003. ABC bacteria are commonly found in soil and water. They sometimes also exist on the skin of healthy people. The bacteria pose little risk to healthy people. However, those with open wounds or weakened immune systems are at greater risk of ABC infection.

Based on a Finnish study, smokers have higher risk of depression than non-smokers. In addition, smokers who quit have an elevated risk of depressive symptoms in the short term.

It is known that depression is associated with cigarette smoking, but the nature of this association has been unclear.

According to the self-medication hypothesis, those who suffer from depressive symptoms smoke cigarettes in order to alleviate their symptoms.

The High Resolution Stereo Camera (HRSC) on board ESA’s Mars Express has captured breathtaking images of the Deuteronilus Mensae region on Mars.

The images were taken on 14 March 2005 during orbit number 1483 of the Mars Express spacecraft with a ground resolution of approximately 29 metres per pixel.

Capturing the coldest atoms in the universe within the confines of a laser beam, University of California, Berkeley, physicists have made a device that can map magnetic fields more precisely than ever before.

Doctors now use sensitive magnetic field detectors called SQUIDS to record faint magnetic activity in the brain, while similar detectors are employed in fields ranging from geology to semiconductor manufacturing.

Patterns of human behavior and movement in crowded cities – the tipping point at which agitated crowds become anti-social mobs, the configuration of civic areas as defensible spaces that also promote free speech, the design of retail space that fosters active walking – are at the core of an immersive 3-D computational model under development by an Arizona State University geographer.

Mathematicians and number buffs have their records. And today, an international team has broken a long-standing one in an impressive feat of calculation.

On March 6, computer clusters from three institutions – the EPFL, the University of Bonn and NTT in Japan -- reached the end of eleven months of strenuous calculation, churning out the prime factors of a well-known, hard-to-factor number that is a whopping 307 digits long.

Studies have shown that gastrointestinal (GI) tract function is often influenced by specific stimulants or reactors, which sometimes cause irritable bowel syndrome (IBS) or constipation. Two studies presented today at Digestive Disease Week® 2007 (DDW®) take a closer look at GI stimulation, including one examining the role of serotonin and reactions to certain types of foods and another looking at the potential therapeutic value of nerve stimulation for constipation. DDW is the largest international gathering of physicians and researchers in the fields of gastroenterology, hepatology, endoscopy and gastrointestinal surgery.