Ever since the relationship between land area and number of species crystallized into a mathematical power function, islands and island archipelagoes have been thought of as biological destinations where species from large continents arrive and, over time, evolve into new species in geographic seclusion.

Since islands have many times fewer species than the continent, it seemed only logical that continents were rich sources from which islands drew only a small sample. Once isolated and with fewer species around, island organisms were thought to lose their competitive edge and so they hardly ever re-colonized the continent from which they originated.

It is highly unlikely that older women generate new eggs, report researchers at the University of South Florida in collaboration with a center in China.

The USF study counters the controversial findings of reproductive endocrinologist Jonathan Tilly, PhD, and his team of Harvard scientists. Tilly's work, published in 2004 in Nature with a follow-up study a year later in Cell, challenged the biological dogma that mammals, including women, are born with a limited lifetime supply of eggs.

XDx, a molecular diagnostics company, today announced its AlloMap® molecular expression test will be the subject of presentations and discussions at the American Transplant Congress 2007.

The test, currently used to detect the absence of heart transplant rejection instead of routine invasive heart muscle biopsies, has now been shown to correlate with oxygen saturation levels, cardiac filling pressures, and the electrical properties of the transplanted heart.

Also, data from the Lung Allograft Rejection Gene expression Observation (LARGO) study presented at the ATC sessions demonstrate that a non-invasive blood test can detect cytomegalovirus-induced immune responses in lung transplant patients.

Researchers at the University of California, San Diego (UCSD) School of Medicine have developed new technology which, combined with proteomics – the large-scale study of the structure and function of proteins and their functions – has allowed them to map an extensive network of the signaling proteins that control cell movement.

Their work, providing the first comprehensive profile of cell movement, could lead to a better understanding of cell migration in cancer metastasis and inflammatory disease.

Researchers at the Department of Energy's Argonne National Laboratory have developed a new approach to increasing the capacity and stability of rechargeable lithium-ion batteries.

The technology is based on a new material for the positive electrode that is comprised of a unique nano-crystalline, layered-composite structure.

A new study showed that a certain form of neuropsin, a protein that plays a role in learning and memory, is expressed only in the central nervous systems of humans and that it originated less than five million years ago.

The human and chimpanzee genomes vary by just 1.2 percent, yet there is a considerable difference in the mental and linguistic capabilities between the two species.

The likelihood of developing bipolar disorder depends in part on the combined, small effects of variations in many different genes in the brain, none of which is powerful enough to cause the disease by itself, a new study shows.

However, targeting the enzyme produced by one of these genes could lead to development of new, more effective medications. The research was conducted by scientists at the National Institutes of Health's National Institute of Mental Health (NIMH), with others from the Universities of Heidelberg and Bonn and a number of U.S. facilities collaborating in a major project called the NIMH Genetics Initiative.

The study is the first to scan virtually all of the variations in human genes to find those associated with bipolar disorder.

The drug trastuzumab (Herceptin) is used to treat HER2-positive breast cancer (a type of breast cancer that overexpresses the HER2 gene and accounts for about 25% of all breast cancers). Trastuzumab therapy improves the chances of survival; however, it has deleterious side effects and is expensive. Thus, it is important to accurately determine the patient’s HER2 status.

The challenge is to develop a testing strategy that is both accurate and economical. A false-negative test result can mean a woman will not receive a life-prolonging drug, and a false-positive result can lead to unnecessary, expensive drug treatment.

Pacific Northwest National Laboratory geologists have put out a call for teeth tusks, femurs and any and all other parts of extinct mammoths left by massive Ice Age floods in southeastern Washington.

New evidence on sex differences in people’s brains and behaviors emerges with the publication of results from the British Broadcasting Corporation’s (BBC) Sex ID Internet Survey. Survey questions and tests focused on participants’ sex-linked cognitive abilities, personality traits, interests, sexual attitudes and behavior, as well as physical traits. The Archives of Sexual Behavior¹ has devoted a special section in its April 2007 issue to research papers based on the BBC data.