A new study suggests how a notorious cancer gene may contribute to tumor growth.

The insight emerged from a long-running study of a protein called PMR1, the key player in an unusual mechanism that cells use to quickly stop production of certain important proteins.

Researchers discovered that PMR1 is activated – or “turned on – by another molecule, an energy-packing protein called Src (pronounced “sark”).

Playground roughhousing has long been a tradition of children and adolescents, much to the chagrin of several generations of parents who worry that their child will be hurt or worse, become accustom to violence and aggression. But animal research may paint a different portrait of rough and tumble play; one that suggests that social and emotional development may rely heavily on such peer interaction.

Nearly one in three women still experience painful sexual intercourse a year after their baby is born and more than half have at least one sex-related health problem, according to research in the March issue of Journal of Clinical Nursing.

482 women who had attended maternity units in Birmingham, UK, took part in a self-administered questionnaire at least a year after their most recent birth.

"87 per cent complained of at least one health problem" says Midwife Amanda Williams, who is currently on secondment to the city's Perinatal Institute.

We take "self-assembly" for granted when it is carried out by the biopolymers which are our hair, teeth, or skin. But when scientists devise new ways for molecules to self assemble into new materials, it is an important achievement.

Researchers with the Macromolecules and Interfaces Institute (MII www.mii.vt.edu) at Virginia Tech report such a development in the online issue for the Journal of the American Chemical Society, in the article, "Aggregation of Rod-Coil Block Copolymers Containing Rigid Polyampholyte Blocks in Aqueous Solution" (10.1021/ja070422+) and at the 233rd National Meeting of the American Chemical Society (ACS) in Chicago, March 25-29.

Maps of the sea surface temperature around Galapagos Islands and Cocos Island in the Pacific Ocean are being produced daily and are available online in full resolution in near-real time as part of the Medspiration project, an ESA-funded effort to represent the most reliable temperature of the seas on a global basis.

Galapagos Islands and Cocos Island have been integrated into Medspiration until 31 March in order to support the study of wildlife migration processes from the two islands as part of ESA’s new Diversity project, which kicked off in January 2007 to support the initiative of the United Nations Convention on Biological Diversity (UNCBD) to reduce significantly the current rate of biodiversity loss by 2010.

A new nanoscale apparatus developed at JILA—a tiny gold beam whose 40 million vibrations per second are measured by hopping electrons—offers the potential for a 500-fold increase in the speed of scanning tunneling microscopes (STM), perhaps paving the way for scientists to watch atoms vibrate in high definition in real time.


This slow-motion simulation of the JILA nanoscale motion detector shows the wiggling of a floppy metal beam, just 100 nanometers thick, as it is struck by an electric current at the dot. Red indicates the greatest change in position from the rest state. Credit: Credit: K. Lehnert/JILA

Psychologists have taken the "media priming" effects of popular video console and PC-based games on the road, finding that virtual racing seems to lead to aggressive driving and a propensity for risk taking. Extending prior findings on how aggressive virtual-shooter games increase aggression-related thoughts, feelings and behaviors, researchers at Munich's Ludwig-Maximilians University and the Allianz Center for Technology found that of 198 men and women, those who play more virtual car-racing games were more likely to report that they drive aggressively and get in accidents. Less frequent virtual racing was associated with more cautious driving.

The American Institute of Mathematics (AIM), one of the leading math institutes in the U.S., announced today that after four years of intensive collaboration, 18 leading mathematicians and computer scientists from the U.S. and Europe have successfully mapped E8, one of the largest and most complicated structures in mathematics. Partners on this project included MIT, Cornell University, University of Michigan, University of Utah and University of Maryland.


The E8 root system consists of 240 vectors in an eight-dimensional space. See what is E8? Those vectors are the vertices (corners) of an eight-dimensional object called the Gosset polytope 421.

New non-toxic and targeted therapies for metastatic breast and ovarian cancers may now be possible, thanks to a discovery by a team of researchers at the University of British Columbia.

In a collaboration between UBC stem cell and cancer scientists, it was found that a protein called podocalyxin – which the researchers had previously shown to be a predictor of metastatic breast cancer – changes the shape and adhesive quality of tumour cells, affecting their ability to grow and metastasize. Metastatic cancer is invasive cancer that spreads from the original site to other sites in the body.

The discovery demonstrated that the protein not only predicted the spread of breast cancer cells, it likely helped to cause it.

To address the high rate of multiple births resulting from in-vitro-fertilization (IVF), researchers at Yale School of Medicine and McGill University have developed a procedure that estimates the reproductive potential of individual embryos, possibly leading to a decrease in multiple-infant births and a higher success rate in women undergoing IVF.

Over 100,000 in-vitro fertilization procedures are performed each year in the United States. In 2002, 3.1 embryos on average were transferred in IVF cycles, but only 34.3 percent resulted in pregnancies. Of those successful pregnancies, 29 percent resulted in multiple births. These statistics remained unchanged within the last decade suggesting that an improvement is needed over the current methodology used for embryo evaluation.