Cancer Research

Cell Cultures In 3D Show Nanoparticle Drug Delivery Results

A nanoparticle drug delivery system designed for brain tumor therapy has shown promising tumor cell selectivity in a novel cell culture model devised by University of Nottingham scientists. Therapy for brain cancers is particularly difficult for a number o ...

Article - News Staff - Aug 23 2007 - 12:11am

P53 Tumor-Suppressor Regulates Trio Of "Junk" RNA Genes

Scientists have shown in literally thousands of studies that the p53 gene deserves its reputation as “the guardian of the genome.” It calls to action an army of other genes in the setting of varied cell stresses, permitting repair of damaged DNA or promoti ...

Article - News Staff - Aug 23 2007 - 9:40pm

Adiponectin And Leptin Hormones Protect Obese Mice From Diabetes

The “world’s fattest mice” can overeat without developing insulin resistance or diabetes thanks to a glut of adiponectin, a hormone that controls sensitivity to insulin, and a lack of leptin, a hormone that curbs appetite- a dichotomy that helps explain wh ...

Article - News Staff - Aug 23 2007 - 9:51pm

UTX-JMJD3 Essential For Stem Cell Development

Researchers at BRIC, University of Copenhagen, have identified a new gene family (UTX-JMJD3) essential for embryonic development. The family controls the expression of genes crucial for stem cell maintenance and differentiation, and the results may contrib ...

Article - News Staff - Aug 24 2007 - 2:02pm

Huntington's Disease Victims Have Too Much REST

Huntington's is an inherited degenerative neurological disease that affects up to 8 people out of every 100,000 in Western countries. Any person whose parent has Huntington's has a 50-50 chance of inheriting the faulty gene that causes it and eve ...

Article - News Staff - Aug 24 2007 - 2:22pm

When Is A Stem Cell Not Really A Stem Cell?

Working with embryonic mouse brains, a team of Johns Hopkins scientists seems to have discovered an almost-too-easy way to distinguish between “true” neural stem cells and similar, but less potent versions. Their finding, reported this week in Nature, coul ...

Article - News Staff - Aug 26 2007 - 5:31pm

Buffer Genes And Ashkenazi Jews Help Uncover The Genetic Components Of Aging

People who live to 100 or more are known to have just as many—and sometimes even more—harmful gene variants compared with younger people. Now, scientists at the Albert Einstein College of Medicine of Yeshiva University have discovered the secret behind thi ...

Article - News Staff - Aug 27 2007 - 9:54am

Cells United Against Cancer

Sheets of highly organized epithelial cells line all the cavities and free surfaces of the body, forming barriers that control the movement of liquids and cells in the body organs. The organized structure of normal breast epithelial cells may also serve as ...

Article - News Staff - Aug 27 2007 - 5:37pm

L1-CAM's Role In How Cancer Metastasizes

Colorectal cancer is one of the most prevalent cancers in the Western world. The tumor starts off as a polyp but then turns into an invasive and violent cancer, which often spreads to the liver. Prof. Avri Ben-Ze’ev and Dr. Nancy Gavert of the Weizmann Ins ...

Article - News Staff - Aug 28 2007 - 12:53am

Some Genetic Impact Of Smoking Irreversible

Only about a fifth of the genes in a cell are switched on at any given time but environmental changes such as smoking lead to changes in that genetic activity. According to a Canadian team led by Wan L. Lam and Stephen Lam from the British Columbia Cancer ...

Article - News Staff - Aug 29 2007 - 2:47pm