Genetics & Molecular Biology

Engineering A Cell Switch

Why should we bother building mathematical models of biological systems? Scientists from other fields might wonder why one would as such a question- physicists, climate scientists, economists, engineers, and chemists all use mathematical models to underst ...

Article - Michael White - Jan 12 2010 - 6:28pm

A Yeast Contribution For The Treatment Of Parkinson’s Disease

Scientists have just identified several molecules capable of reversing the brain abnormalities of Parkinson’s disease (PD), while also uncovering new clues for its origin in a study just published in the journal Disease Models and Mechanisms (1). PD is ch ...

Article - Catarina Amorim - Jan 12 2010 - 5:46pm

Higher Levels Of Hsp70 Restore Mutant Proteins

Using proteosome inhibitors to trick cells into producing a chaperone protein called Hsp70 may be one way of enhancing the natural ability of cells to restore their own mutant proteins. Researchers at the Fox Chase Cancer Center say the discovery may help ...

Article - News Staff - Jan 15 2010 - 12:22pm

The Math Behind A Cell Switch

Earlier this week I argued that biological systems posses dynamical properties that are biologically important, and understandable primarily through mathematical modeling. As an example, I discussed a paper that explored the advantages of double positive ...

Article - Michael White - Jan 15 2010 - 4:51pm

Cancer Initiating Stem Cells Suppress Immune Response To Brain Tumor And The Role Of STAT3 Pathway In Immunosuppression

Cancer-initiating cells that launch glioblastoma multiforme, the most lethal type of brain tumor, also suppress an immune system attack on the disease, scientists from The University of Texas M. D. Anderson Cancer Center report in a paper featured on the ...

Article - flower 5 - Jan 25 2010 - 2:14pm

Epigenetic Mechanism Behind The Most Malignant Of All Brain Tumours

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Article - Catarina Amorim - Jan 18 2010 - 1:01am

Biomedical Science In 2020

What will geneticists and molecular cell biologists be doing in 2020? 10 years ago, genomic technologies like DNA microarrays were just beginning to change the way molecular biologists worked, and the draft sequence of the human genome was a year from publ ...

Article - Michael White - Jan 17 2010 - 10:38pm

Attacking 14α-Demethylase May Help Treat Sleeping Sickness

Reporting in the Journal of Biological Chemistry, an international team of researchers has determined the structure of 14α-Demethylase (14DM), an enzyme essential to the survival of the protozoan parasites that cause sleeping sickness, Chagas disease and l ...

Article - News Staff - Jan 18 2010 - 1:09pm

Plastid transcription technologies: bacterial core with eukaryotic extension.

Chloroplasts are photosynthetic organelles containing a part of plant genome usually called plastome. Introduction of foreign genes into plastids and creation of transplastomic plants has some advantages over classic nuclear transformation, so chloroplasts ...

Blog Post - Ashwani Kumar - Jan 19 2010 - 1:10am

How Ebola Hoodwinks Host Cells

 Iowa State University researchers say they have discovered how the Ebola Virus is able to elude the immune response of host cells that it invades. The problem has stumped scientists for many years, and in a new study published in Nature Structural and Mol ...

Article - News Staff - Jan 19 2010 - 6:05pm