Pharmacology

Kava has been used in ceremonies and for recreational and social purposes in the South Pacific since ancient times, much like alcohol, tea or coffee is in other societies today. In the 1980s other…

Drug treatments for depression can take many weeks for the beneficial effects to emerge. The excruciating and disabling nature of depression highlights the urgency of developing treatments that act…

A paper by Professor Fabrizio Schifano at the University of Hertfordshire’s School of Pharmacy, which has been published in the Journal of Psychopharmacology, indicates that 1,022 people died between…

Contrary to some reports, the epilepsy drug oxcarbazepine does not appear to prevent migraine, according to research published in the February 12, 2008, issue of Neurology®, the medical journal of…

A new study documents malformations seen in an infant born to a kidney transplant recipient who had taken mycophenolate mofetil (MMF), a widely used immunosuppressant available commercially as…

February’s issue of Pediatrics offers a study saying there is reason to rethink blaming the spike in autism diagnoses on thimerosal, a mercury-containing preservative routinely used in several…

A new study sheds light on the relationship between women who smoke while pregnant — or are exposed to second-hand smoke — and an increased risk of SIDS to their babies. Researchers at McMaster…

Daily consumption of caffeine in coffee, tea or soft drinks increases blood sugar levels for people with type 2 diabetes and may undermine efforts to control their disease, say scientists at Duke…

The results are in. Jiri Gut from the Rosenthal group has run 2 of our Ugi products and they both show inhibition of falcipain-2 (EXP165) and Plasmodium falciparum (EXP166) in the micromolar range.…

COX-2 inhibitors are having a tough year. Vioxx was withdrawn voluntarily a few months ago and now Celebrex, the arthritis drug that blocks pain by inhibiting the COX-2 enzyme, has been shown in…