If a vaccine requires cold storage for shipping, many areas where infrastructure doesn't hold up are unable to receive them. A possible solution to this problem is a mobile vaccine printer that could produce hundreds of vaccine doses in a day.
The printer produces patches with hundreds of microneedles containing the vaccine. The patches can be attached to the skin, allowing the vaccine to dissolve without the need for a traditional injection. Once printed, the vaccine patches can be stored for months at room temperature.
In their paper, the scientists used the printer to produce thermostable Covid-19 RNA vaccines that could induce a comparable immune response to that generated by injected RNA vaccines, in mice.