Comparison of real-time PCR and blood culture for the diagnosis of bloodstream infections in onco-hematologic patients.
Objectives.Sepsis is a syndrome that results from a dysregulated host response to infection which can rapidly lead to organ dysfunction and death.The aim of this study was the microbiological and clinical assessment of a new real-time PCR test (SeptiFast: SF, Roche Diagnostics) for the diagnosis of blood stream infections (BSI) in a population of neutropenic patients.The results of SF were compared with blood cultures (BC) obtained on the same specimens and the clinical significance of the two methods was assessed. Methods.