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What Next For Messenger RNA (mRNA)? Maybe Inhalable Vaccines

No one likes getting a needle but most want a vaccine. A new paper shows progress for messenger...

Toward A Single Dose Smallpox And Mpox Vaccine With No Side Effects

Attorney Robert F. Kennedy Jr. and his US followers over the last 25 years have staunchly opposed...

ChatGPT Is Cheaper In Medicine And Does Better Diagnoses Even Than Doctors Using ChatGPT

General medicine, routine visits and such, have gradually gone from M.D.s to including Osteopaths...

Even After Getting Cancer, Quitting Cigarettes Leads To Greater Longevity

Cigarettes are the top lifestyle risk factor for getting cancer, though alcohol and obesity have...

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A new system called BASIC could give synthetic biology a boost by creating artificial DNA that is faster, more accurate and more flexible than existing methods. 

To engineer new organisms, scientists build artificial genes from individual molecules and then put these together to create larger genetic constructs which, when inserted into a cell, will create the required product. Various attempts have been made to standardisz the design and assembly process but, until now, none have been completely successful. 
A study has found new evidence linking genetic factors associated with autism to better cognitive ability in people who do not have the condition - which means like many things in genetics it could be a small variation that separates a benefit from a detriment.

Autism is a disability often marked by significant language and speech difficulties but there is no firm relationship between autism and intelligence. Up to 70 percent of individuals with autism do have an intellectual disability but some people with the disorder have well-preserved, or even higher than average, non-verbal intelligence. Non-verbal intelligence is how people solve complex problems using visual and hands-on reasoning skills with little or no use of language.   
Researchers have detected about 20 rotating dust and gas discs in two clusters hosting exceptionally large and hot stars. The science mystery is how the rotating discs are able to withstand evaporation under such extreme conditions - if there is a Hell, this must certainly be it.

The center of the Milky Way is a nursery for young stars: In its heart, more young stars are born in dark clouds than in any other place in the Galaxy. These stars form in rich groups such as the 'Quintuplet' and 'Arches' clusters. Both star clusters are only a few million years old and contain stars as massive as 100 times the mass of the Sun. 

Salt-loving, halophilic, microbes could donate proteins to clean up radioactive strontium and caesium ions from the Fukushima Dai-ichi Nuclear Power Plant incident in Japan.

The X-ray structure of a beta-lactamase enzyme from one such microbe, the halophile Chromohalobacter sp. 560, shows it has highly selective cesium binding sites.  A 1.8 to 2.9 angstrom resolution structure for this enzyme. Anomalous X-ray diffraction also revealed binding sites in the protein for Sr2+ and Cs+ ions, the team reports.

Baby it’s warm inside … we have 200 microbes for every human cell. Agricultural Research Service

We are all populated by microbes – helpful or otherwise – which form a community known as a microbiome. Recent research by Ryan Newton and co-workers has shown that sewage-based analysis of the human microbiome can be used to diagnose health issues at a population level.

Statins are associated with increased risk for diabetes, though it is unclear why. One hypothesis is that statins increase expression of LDL receptors and increase cholesterol uptake into cells including the pancreas, which could cause pancreatic dysfunction. Familial hypercholesterolemia causes decreased LDL transport into cells and researchers have hypothesized that with familial hypercholesterolemia, decreased pancreatic LDL transport would lessen cell death and ultimately lead to lower rates of diabetes.