Sepsis causes 11 million deaths annually so preventing that requires prompt recognition, source control, antibiotics, fluids and vasopressors.

Sometimes adjunctive therapies such as orticosteroids help but the science is inconclusive. A recent study was designed to evaluate the role of corticosteroids in the management of patients with septic shock and the contradictory effects on mortality as recorded in past research and treatment.

In recent geological history, 90,000 of every 100,000 years have been ice ages. It's been 12,000 years since the last one so we may be due.

Or not. Climate science has a few rules but a lot of exceptions and 700,000 years ago a big exception occurred. At that time the planet experienced a “warm ice age” and it permanently changed the climate cycles on Earth. Though it became warmer and with more rain, the polar glaciers also expanded. Geological data in combination with computer simulations published in Nature Communications hopes to lend insight into this paradox.

Screening is underway to find a patient for the world's first bladder transplant in humans. 

If a vaccine requires cold storage for shipping, many areas where infrastructure doesn't hold up are unable to receive them. A possible solution to this problem is a mobile vaccine printer that could produce hundreds of vaccine doses in a day.

The printer produces patches with hundreds of microneedles containing the vaccine. The patches can be attached to the skin, allowing the vaccine to dissolve without the need for a traditional injection. Once printed, the vaccine patches can be stored for months at room temperature.

In their paper, the scientists used the printer to produce thermostable Covid-19 RNA vaccines that could induce a comparable immune response to that generated by injected RNA vaccines, in mice.

New results show that the number of reported cancer cases in the National Cancer Database during the COVID-19 pandemic declined by 14.4 percen, which means over 200,000 cancer cases were not diagnosed and/or treated.

The reasons were unclear, perhaps concern about catching COVID-19 or being symptomatic but not wanting to go to the doctor because of media claims about those unable to get care for SARS-CoV-2. The results are more obvious; a lot of people are at greater risk. 

New research shows that dairy products have made life easier for thousands of years. Even in places that are a challenge for anyone, like the Tibetan Plateau - the “roof of the world.”

Genetic engineering due to natural selection at several genomic loci certainly made early Tibetans better able to survive high elevations, but those did nothing for calorie requirements. A new study finds that dairy made it possible. Ancient proteins from the dental calculus of 40 human individuals from 15 sites across the interior plateau show that dairying was introduced onto the hinterland plateau by at least 3,500 years ago.