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What Next For Messenger RNA (mRNA)? Maybe Inhalable Vaccines

No one likes getting a needle but most want a vaccine. A new paper shows progress for messenger...

Toward A Single Dose Smallpox And Mpox Vaccine With No Side Effects

Attorney Robert F. Kennedy Jr. and his US followers over the last 25 years have staunchly opposed...

ChatGPT Is Cheaper In Medicine And Does Better Diagnoses Even Than Doctors Using ChatGPT

General medicine, routine visits and such, have gradually gone from M.D.s to including Osteopaths...

Even After Getting Cancer, Quitting Cigarettes Leads To Greater Longevity

Cigarettes are the top lifestyle risk factor for getting cancer, though alcohol and obesity have...

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Nearly 30 years ago, scientists agreed that for clinical trial results to be valid for both sexes, they needed more women.

Yet women seem to be a lot less likely to sign up for clinical trials for cardiovascular disease. The authors of a new paper outline the issue as to why:

Differential Care – Low rates of referral to cardiologists and specialty programs for more aggressive care might lead to fewer women being treated by specialists recruiting for clinical trials.
A fearsome beast soared above the ancient, vast inland sea once that once covered covering much of outback Queensland. This newly found pterosaur, named Thapunngaka shawi, was discovered in Wanamara Country, near Richmond in North West Queensland.

It's the stuff of nightmares, with a spear-like mouth containing 40 giant teeth and a wingspan around 20 feet.

We may imagine it to be like a big bird or a bat but that is not so, according to University of Queensland doctoral student Tim Richards: "Pterosaurs were a successful and diverse group of reptiles – the very first back-boned animals to take a stab at powered flight.”

Light that goes into that black hole doesn’t come out, so we shouldn’t be able to see anything behind one, but if a black hole is warping space, bending light and twisting magnetic fields around itself, then according to Einstein's theory of general relativity direct observation of light from behind a black hole should be possible.

Now it has happened

Material falling into a supermassive black hole powers the brightest continuous sources of light in the universe, and as it does so, forms a corona around the black hole. This light – which is X-ray light – can be analyzed to map and characterize a black hole.
Smartphones tout 'dark mode' as an energy-saving feature, because darker-colored pixels use less power than lighter-colored pixels.

It's mostly an intellectual placebo, finds a new study, because of the way most people use their phones on a daily basis. The study looked at six of the most-downloaded apps on Google Play: Google Maps, Google News, Google Phone, Google Calendar, YouTube and Calculator. The researchers analyzed how dark mode affects 60 seconds of activity within each of these apps on the Pixel 2, Moto Z3, Pixel 4 and Pixel 5.
A recent blood group analysis of three Neanderthals and one Denisovan confirm their African origin, Eurasian dispersal, and interbreeding with early Homo sapiens. Intriguingly, it also added evidence of low genetic diversity and possible demographic fragility.

Neanderthals and Denisovans are extinct hominin lineages but were present throughout Eurasia from 300,000 to 40,000 years ago. This paper isn't the first time they have been sequenced but using the genes underlying blood groups in previously sequenced genomes of one Denisovan and three Neanderthal females who lived 100,000 to 40,000 years ago allowed scholars to identify their blood groups.
Blood pressure is a risk factor for a heart event and angiotensin-converting enzyme (ACE) inhibitors and angiotensin receptor blockers (ARBs) are common prescriptions.

Both types of medicines work on the renin-angiotensin-aldosterone system, a group of related hormones that act together to regulate blood pressure. ACE inhibitors lower blood pressure by blocking an enzyme early in the system so that less angiotensin, a chemical that narrows blood vessels, is produced, and blood vessels can remain wider and more relaxed. ARBs block receptors in the blood vessels that angiotensin attaches to, diminishing its vessel-constricting effect.