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'Virtual' mouse brains now available online

'Virtual' mouse brains now available online

A multi-institutional consortium including Duke University has created startlingly crisp 3-D microscopic views of tiny mouse brains -- unveiled layer by layer -- by extending the capabilities of conventional magnetic resonance imaging.
"These images can be more than 100,000 times higher resolution than a clinical MRI scan," said G. Allan Johnson, Duke's Charles E. Putman Distinguished Professor of radiology and professor of biomedical engineering and physics.

These animated micro-CT based images show the moving blood in the left ventricle (LV) of a mouse heart during one heartbeat. The temporal resolution is 10 ms and the spatial resolution is 100 microns on all axes.

Stellar Tiramisu

Stellar Tiramisu

Looking at the chemical composition of stars that host planets, astronomers have found that while dwarf stars often show iron enrichment on their surface, giant stars do not. The astronomers think that the planetary debris falling onto the outer layer of the star produces a detectable effect in a dwarf star, but this pollution is diluted by the giant star and mixed into its interior.
"It is a little bit like a Tiramisu or a Capuccino," says Luca Pasquini from ESO, lead-author of the paper reporting the results. "There is cocoa powder only on the top!'
Just a few years after the discovery of the first exoplanet it became evident that planets are preferentially found around stars that are enriched in iron.

How Neutral Genetic Drift Shaped Our Genome

How Neutral Genetic Drift Shaped Our Genome

Johns Hopkins researchers have added to the growing mound of evidence that many of the genetic bits and pieces that drive evolutionary changes do not confer any advantages or disadvantages to humans or other animals.
“For a long time, the basic belief of evolution was that all random genetic changes that manage to stick around have some selective advantage,” says Nicholas Katsanis, Ph.D., Associate Professor at Hopkins’ Institute of Genetic Medicine. “But our work adds to the case that frequently, we are what we are largely due to random changes that are completely neutral.”

Could Global Warming Lead To Global Warring?

Could Global Warming Lead To Global Warring?

By looking at temperature fluctuations and reduced agricultural production in eastern China's past, David Zhang from the University of Hong Kong and his colleagues say they can predict the geopolitics of global warming's future.
They found that warfare frequency in eastern China, and the southern part in particular, significantly correlated with temperature oscillations. Almost all peaks of warfare and dynastic changes coincided with cold phases.
Looking to the future and applying their findings, Zhang and colleagues suggest that shortages of essential resources, such as fresh water, agricultural land, energy sources and minerals may trigger more armed conflicts among human societies.

Fossilized Midges Show Proof Of Unstable Climate

Fossilized Midges Show Proof Of Unstable Climate

Fossilised midges have helped scientists at the University of Liverpool identify two episodes of abrupt climate change that suggest the UK climate is not as stable as previously thought.
The episodes were discovered at a study in Hawes Water in Northern Lancashire, where the team used a unique combination of isotope studies and analysis of fossilised midge heads. Together they indicated where the climate shifts occurred and the temperature of the atmosphere at the time.
The first shift detected occurred around 9,000 years ago and the second around 8,000 years ago. Evidence suggests that these shifts were due to changes in the Gulf Stream, which normally keeps the UK climate warm and wet.

Sugar Can Help You Lose Waist

Sugar Can Help You Lose Waist

A few years ago, the low-carb diet craze was in full force and it looked like sugar might never return to society's good graces.
Sugar substitutes are a billion-dollar business. According to a national survey conducted by the Calorie Control Council, a sugar-substitute industry group based in Atlanta, 80 percent of adults use low-calorie and sugar-free foods and beverages.
Yet you can't really count sugar out. For one thing, every diet program recommends sugar substitutes, which keeps the taste of sugar in the minds of its dieters, and though that doesn't make a lot of sense because it's like Alcoholics Anonymous telling its members to drink non-alcoholic beer, it means that people prefer it.

Even American Horses Are Getting Obese

Even American Horses Are Getting Obese

First the obesity problem in humans alarmed physicians and then veterinarians worried about fat cags ( and dogs) but now a team of researchers in the Virginia-Maryland Regional College of Veterinary Medicine and Virginia Tech has determined that horses are also facing serious health risks because of obesity.
Fifty-one percent of the horses evaluated during the pioneering research were determined to be overweight or obese – and may be subject to serious health problems like laminitis and hyperinsulinemia. And just like people, it appears as though the culprits are over-eating and lack of exercise.

Birds And Bees - Why Flowers Have Pretty Colors

Birds And Bees - Why Flowers Have Pretty Colors

Unlike moths and butterflies that are often brilliantly colored to warn potential predators that they carry toxins, flowers and the fruits they produce have brilliant colors to attract the attention of pollinators and frugivores who will disperse their pollen and seed, thus guaranteeing the next generation.
The appearance of flowering plants on earth about 150 million years ago had a profound effect on the evolution of many other kinds of organisms like insects, birds, and mammals, who became the pollinators and consumers of those plants, thus ensuring the continuity of both the plant and its animal partner.

Scientists identify 2 distinct Parkinson's networks

Scientists identify 2 distinct Parkinson's networks

The disease that causes tremors, rigidity and slowed movements in a million Americans also targets another brain network that regulates cognitive thought and the ability to carry out everyday tasks.
David Eidelberg, MD, head of the Center for Neurosciences at The Feinstein Institute for Medical Research, and his colleagues measured and quantified this network of brain regions during a five-year study of newly diagnosed Parkinson’s patients who agreed to be followed several times over the course of the study. This is the first longitudinal study of Parkinson’s disease using a brain scan to follow these Parkinson’s network over time.

Penn researchers discover how microRNAs control protein synthesis

Penn researchers discover how microRNAs control protein synthesis

While most RNAs work to create, package, and transfer proteins as determined by the cell’s immediate needs, miniature pieces of RNA, called microRNAs (miRNAs) regulate gene expression. Recently, researchers from the University of Pennsylvania School of Medicine determined how miRNAs team up with a regulatory protein to halt protein production.
Scientists estimate miRNAs have the ability to regulate the expression of approximately one third of human genes, and previous studies have linked abnormal activity of miRNAs to cancer and other diseases.

Breast Cancer And Race

Breast Cancer And Race

A study of more than 2,200 women at the Kimmel Cancer Center at Jefferson in Philadelphia shows that African American women have more advanced breast cancer at the time of diagnosis than Caucasian women.
In addition, African American women tend to have breast cancer tumor types that are more aggressive and have poorer prognoses.

PIF 4 and PIF 5 Regulate The Cycle Of Plants

PIF 4 and PIF 5 Regulate The Cycle Of Plants

Most plants and animals show changes in activity over a 24-hour cycle. Now, for the first time, researchers have shown how a plant combines signals from its internal clock with those from the environment to show a daily rhythm of growth.
Using time-lapse photography, postdoctoral researcher Kazunari Nozue, with colleagues from UC Davis and the University of Lausanne, Switzerland, found that the shoots of Arabidopsis seedlings show a spurt of growth once a day.
The timing of that growth spurt is controlled by both the plant's internal clock and by exposure to light, acting on two genes called PIF 4 and PIF 5.