More men than women develop Parkinson’s disease and new work presented at the Federation of European Neuroscience Societies says that it is do to sex differences in how brain cells change. Parkinson’s disease affects about 9 million people and becomes increasingly prevalent with age.
SILVER SPRING, Md. - The Walter Reed Army Institute of Research (WRAIR) and collaborators at the Beth Israel Deaconess Medical Center and Harvard Medical School have completed a promising preclinical study of two Zika vaccine candidates that suggests that an effective human vaccine will be achievable. Findings from the study were published today in the journal Nature.
In the preclinical study, WRAIR and the Beth Israel Deaconess Medical Center tested two Zika virus vaccine candidates: a DNA vaccine developed at Harvard based on a Zika virus strain isolated in Brazil, and a purified inactivated virus vaccine developed at WRAIR based on a Zika virus strain isolated in Puerto Rico.
A single dose of either of two experimental Zika vaccines fully protected mice challenged with Zika virus four or eight weeks after receiving the inoculations. The research, conducted by investigators supported by the National Institute of Allergy and Infectious Diseases (NIAID), part of the National Institutes of Health, suggests that similar vaccines for people could be similarly protective.
Species across the world are rapidly going extinct due to human activities, but humans are also causing rapid evolution and the emergence of new species. A new study published today summarises the causes of manmade speciation, and discusses why newly evolved species cannot simply replace extinct wild species. The study was led by the Center for Macroecology, Evolution and Climate at the University of Copenhagen.
A common close partnership which sees baby fish sheltering from predators among the poisonous tentacles of jellyfish will be harmed under predicted ocean acidification, a new University of Adelaide study has found.
Published today in the journal Proceedings of the Royal Society B, the researchers say that modification of this baby fish-jellyfish symbiotic relationship is likely to lead to higher mortality among the affected fish species which include some of the common commercial fish. A well-known example of marine symbiosis is the relationship between anemones and clown-fish, popularised in the animated movie, Finding Nemo.
A period of intense debate about statins, covered widely in the mainstream media, was followed by a substantial rise in the proportion of people in the UK stopping taking the drug, according to a new study by the London School of Hygiene & Tropical Medicine.
Led by the London School of Hygiene & Tropical Medicine and funded by the British Heart Foundation, the study by Anthony Matthews and colleagues is the first to attempt to quantify how the controversy questioning the risk-benefit balance for statins, reflected by the UK media, may have affected the use of the drug in primary care.
Philadelphia, June 28, 2016 - A new national survey by Health Union of more than 1,000 individuals with Irritable Bowel Syndrome (IBS) reveals that the condition is difficult to diagnose and often even more difficult to treat. Respondents often found healthcare providers and the public in general lacking in empathy and understanding of the full impact of the disease. Self-treatment often becomes the norm and controlling symptoms difficult.
In a study appearing in the June 28 issue of JAMA, Christiane E. Angermann, M.D., of University Hospital Wurzburg, Germany, and colleagues examined whether 24 months of treatment with the antidepressant escitalopram would improve mortality, illness, and mood in patients with chronic heart failure and depression.
In a study appearing in the June 28 issue of JAMA, Peter E. Morris, M.D., of the University of Kentucky, Lexington, and colleagues compared outcomes for standardized rehabilitation therapy to usual intensive care unit (ICU) care for acute respiratory failure.
La Jolla, Calif., June XX, 2016 (embargoed until 11:00 A.M. EST) -- A new study led by scientists at the Sanford Burnham Prebys Medical Discovery Institute (SBP) describes a technology that could lead to new therapeutics for traumatic brain injuries. The discovery, published today in Nature Communications, provides a means of homing drugs or nanoparticles to injured areas of the brain.
"We have found a peptide sequence of four amino acids, cysteine, alanine, glutamine, and lysine (CAQK), that recognizes injured brain tissue," said Erkki Ruoslahti, M.D., Ph.D., distinguished professor in SBP's NCI-Designated Cancer Center and senior author of the study. "This peptide could be used to deliver treatments that limit the extent of damage."
MADISON, Wis. -- University of Wisconsin-Madison researchers studying monkeys have shown that one infection with Zika virus protects against future infection, though pregnancy may drastically prolong the time the virus stays in the body.
The researchers, led by UW-Madison pathology Professor David O'Connor, published a study today (June 28, 2016) in the journal Nature Communications describing their work establishing rhesus macaque monkeys at the Wisconsin National Primate Research Center as a model for studying the way Zika virus infections may progress in people.
Alcohol consumption in Australia has declined steadily during the past decade, with per capita consumption in 2013-14 reaching its lowest level since the early 1960s. A new study published today by the scientific journal Addiction shows that the overall decline in drinking is due mainly to less drinking among people in their teens and early twenties.
BUFFALO, N.Y. - Most people recoil at the thought of ingesting E. coli. But what if the headline-grabbing bacteria could be used to fight disease?
Researchers experimenting with harmless strains of E. coli - yes, the majority of E. coli are safe and important to healthy human digestion - are working toward that goal. Specifically, they have developed an E. coli-based transport capsule designed to help next-generation vaccines do a more efficient and effective job than today's immunizations.
