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How Parasitic Worms Help Minimize Inflammatory Bowel Disease

How Parasitic Worms Help Minimize Inflammatory Bowel Disease

Intestinal worms beneficially influence the composition of gut microbiota in the presence of inflammatory bowel disease, a new study suggests. The findings provide important insights into how intestinal worms, or helminths, manipulate the gut microbiota in a way that is beneficial for its host. Building upon previous research, Deepshika Ramanan and colleagues found that mice deficient in the gene Nod2, which are used to model Crohn's disease, develop abnormalities in their small intestines, including a compromised layer of mucus and changes to intestinal cell morphology. These alterations allowed for greater colonization by the bacteria Bacteroides vulgatus.

Yeast Study Charts Survival Impact Of Genetic Mutations

Yeast Study Charts Survival Impact Of Genetic Mutations

Scientists have mapped how thousands of genetic mutations can affect a cell's chances of survival.
The study involving yeast reveals how different combinations of mutations in a single gene can influence whether the cell lives or dies.
It is the first time scientists have been able to measure the effects of every possible combination of mutations in a gene.

Physicists Build Engine Consisting Of One Atom

Physicists Build Engine Consisting Of One Atom

An article in the latest edition of the journal Science describes an innovative form of heat engine that operates using only one single atom. The engine is the result of experiments undertaken by the QUANTUM work group at the Institute of Physics of Johannes Gutenberg University Mainz (JGU) in collaboration with theoretical physicists of Friedrich-Alexander-Universität Erlangen-Nürnberg (FAU).
Heat engines have played an important role in shaping society ever since the Industrial Revolution. As in the case of motor vehicle engines, they transform thermal energy into mechanical force, and our modern lifestyle would be impossible without them. At the same time, progress in miniaturization is resulting in the creation of ever smaller devices.

Immune Cells Help The Brain To Self-heal After A Stroke

Immune Cells Help The Brain To Self-heal After A Stroke

After a stroke, there is inflammation in the damaged part of the brain. Until now, the inflammation has been seen as a negative consequence that needs to be abolished as soon as possible. But, as it turns out, there are also some positive sides to the inflammation, and it can actually help the brain to self-repair.
"This is in total contrast to our previous beliefs", says Professor Zaal Kokaia from Lund University in Sweden.

For Women, Waiting To Have Children Until After 30 Minimizes Career Income Losses

For Women, Waiting To Have Children Until After 30 Minimizes Career Income Losses

Working women who want to minimize career income losses related to motherhood should wait until they are about 30 years old to have their first children, suggests new research from Washington University in St. Louis.
The findings, published in PLOS ONE, hold true regardless of whether a woman has earned a college degree.
For college graduates and those without a college degree, the researchers found lower lifetime incomes for women who gave birth for the first time at age 30 or younger. The hit was particularly stark for women without college degrees who had their first children before age 25.

'Weirdest Martensite': Century-old Smectic Riddle Finally Solved

'Weirdest Martensite': Century-old Smectic Riddle Finally Solved

ITHACA, N.Y. - Using the latest computer game technology, a Cornell-led team of physicists has come up with a "suitably beautiful" explanation to a puzzle that has baffled researchers in the materials and theoretical physics communities for a century.
Physics professor James Sethna has co-authored a paper on the unusual microstructure of smectics - liquid crystals whose molecules are arranged in layers and form ellipses and hyperbolas - and their similarity to martensites, a crystalline structure of steel.
In fact, Sethna and his cohorts have termed smectic liquids "the world's weirdest martensite."

Why Education Doesn't Bring Women Equal Pay

Why Education Doesn't Bring Women Equal Pay

Women are closing the education gap with men, but a global study of gender equality shows these advances are failing to bring equal access to quality jobs and government representation.
The study, which explored decades of data from more than 150 countries, finds that women have reached 91 percent of the education that men have - but only 70 percent of their rate of employment, and just 25 percent of political representation.
The findings challenge the assumption that education--a hallmark of international development efforts--translates into equal access to high-paying jobs, and suggest greater policy interventions are required to close political and workplace gender gaps.

High-volume Lung Transplant Centers Have Lower Costs And Readmissions

High-volume Lung Transplant Centers Have Lower Costs And Readmissions

High-volume lung transplant centers have lower transplantation costs and their patients are less likely to be readmitted within 30 days of leaving the hospital following surgery, according to a new study of more than 3,000 Medicare patients who received lung transplants.
"The Effect of Transplant Center Volume on Cost and Readmission in Medicare Lung Transplant Recipients" was published online ahead of print in the Annals of the American Thoracic Society.
Previous research established that patient survival is higher at high-volume lung transplant centers. It is unknown, however, whether these better outcomes require more resources or result from better care delivery that might require fewer resources.

By Age 3 Environmental Factors Are Relevant To The Development Of Self-control

By Age 3 Environmental Factors Are Relevant To The Development Of Self-control

University of Texas at Arlington researchers have found that by age 3 environmental influences such as parenting are relevant factors in the development of toddlers' self-control when they are asked not to do something they want to do, such as run into the street or eat a forbidden snack.
"Understanding the development of self-control mechanisms is vital as individuals with low levels of inhibitory control develop more cognitive and socio-emotional development issues, including attention deficit hyperactivity disorder or ADHD," said Jeffrey Gagne, an assistant professor of psychology in UTA's College of Science and co-author of the study.

Potential Cholesterol-lowering Drug Molecule Has Prostate Cancer Fighting Capabilities

Potential Cholesterol-lowering Drug Molecule Has Prostate Cancer Fighting Capabilities

COLUMBIA, Mo. - Standard treatment for prostate cancer can include chemotherapy that targets receptors on cancer cells. However, drug-resistant cancer cells can emerge during chemotherapy, limiting its effectiveness as a cancer-fighting agent. Researchers at the University of Missouri have proven that a compound initially developed as a cholesterol-fighting molecule not only halts the progression of prostate cancer, but also can kill cancerous cells.

Juvenile Offenders Probably More Criminal To Begin With

Juvenile Offenders Probably More Criminal To Begin With

DURHAM, N.C. -- It's a long-simmering debate in juvenile justice: Do young offenders become worse because of their experience with the justice system, or are they somehow different than people who don't have their first criminal conviction until later in life?
"There seems to be a lot of evidence that people who are convicted early are more heavily involved in crime," says postdoctoral researcher Amber Beckley at Duke University, who has a new study out on the topic that appears online in the Journal of Criminal Justice.
Using data from a study that has tracked nearly 1,000 New Zealanders from birth to age 38, Beckley looked at patterns that would distinguish youthful offenders from what she calls "adult-onset offenders."

Heavy Cannabis Use Associated With Reduced Dopamine Release In Brain

Heavy Cannabis Use Associated With Reduced Dopamine Release In Brain

New York, NY, April 14, 2016. In a recent study, researchers found evidence of a compromised dopamine system in heavy users of marijuana. Lower dopamine release was found in the striatum - a region of the brain that is involved in working memory, impulsive behavior, and attention. Previous studies have shown that addiction to other drugs of abuse, such as cocaine and heroin, have similar effects on dopamine release, but such evidence for cannabis was missing until now.