Medication is an important part of treatment for many patients with major depressive disorder, but the transition to antidepressants isn't always smooth.

It can take six weeks for a person to respond to pharmacotherapy. And with remission rates at about only one-third, the majority of patients with depression could also benefit from better overall response to medication.

Researchers at the University of Michigan who specialize in both psychiatry and sleep medicine found a potential way to help. A precise sleep schedule could affect antidepressant remission rates and response time, researchers found. But not in the way they thought.

A new car is a big expense for anyone -- but it will cost some people more than others, even at the same dealership.

A new U of T study, which is the first of its kind to reliably show large differences in the price paid for a new car, reveals that age and even in some cases gender can be a factor.

"We were surprised by the magnitude of the difference in how much people paid for an identical car that was bought in the same month in even the same city," says Ambarish Chandra, Assistant Professor of Business Economics in U of T Scarborough's Department of Management and the Rotman School of Management.

Sexually active transgender youth have pregnancy rates similar to their non-transgender peers--dispelling the notion that trans youth are less at risk for pregnancy, according to new UBC research.

In the first study of its kind, researchers used data from the 2014 Canadian Transgender Youth Health Survey, focusing on a subset of 540 youth aged 14-25 who had previously had sex. They found that five per cent (26) had been involved in a pregnancy at least once - comparable to B.C.'s pregnancy rate of about five per cent among sexually active young people.

The solar system could be thrown into disaster when the sun dies if the mysterious 'Planet Nine' exists, according to Dr. Dimitri Veras in the Department of Physics at University of Warwick, who says he has discovered that the presence of Planet Nine - the hypothetical planet which may exist in the outer Solar System - could cause the elimination of at least one of the giant planets after the sun dies, hurling them out into interstellar space through a sort of 'pinball' effect.

When the sun starts to die in around seven billion years, it will blow away half of its own mass and inflate itself -- swallowing the Earth -- before fading into an ember known as a white dwarf. This mass ejection will push Jupiter, Saturn, Uranus and Neptune out to what was assumed a safe distance.

Researchers from Vrije Universiteit Amsterdam and Radboud University Nijmegen found proof that psychopathic individuals can feel fear, but have trouble in the automatic detection and responsivity to threat. For many decades fear has been put forth as a hallmark feature of psychopathy, the impairments in which would lead to bold risk-taking behavior. Sylco Hoppenbrouwers (VU Amsterdam), Erik Bulten and Inti Brazil (Radboud University) reviewed theoretical and empirical brain and behavioral data pertaining to fear and psychopathy and found that psychopathic individuals have trouble detecting threats. There was however little evidence that the conscious experience of fear was affected, indicating that the experience of fear may not be completely impaired in psychopathy.

DURHAM, N.C. -- All humans are 99.9 percent identical, genetically speaking. But that tiny 0.1 percent variation has big consequences, influencing the color of your eyes, the span of your hips, your risk of getting sick and in some ways even your earning potential.

Although variants are scattered throughout the genome, scientists have largely ignored the stretches of repetitive genetic code once dismissively known as "junk" DNA in their search for differences that influence human health and disease.