Scientists have reported that an experimental vaccine targeting one of the most common genetic drivers of pancreatic cancer, called mutant KRAS, is safe and generated a durable immune responses aimed at preventing the cancer.
While use of well-established medicine has declined among rich, liberal elites in America's wealthiest, most educated states, untested and sometimes dangerous herbal dietary supplement sales in the United States rose to $6,000,000,000 - an increase of 7.9% over 2013.As expected, sales in "natural" food stores were strongest, rising by 8.8%, but even regular food and drug stores had a 7.7% over 2012 sales, reflecting a growing distrust of science among the organic and alternative medicine communities.
Enrollment in a randomized Phase II clinical trial of Pracinostat in combination with azacitidine in patients with previously untreated intermediate-2 or high-risk myelodysplastic syndrome (MDS) has been completed. The multi-center, placebo-controlled, double-blind study enrolled a total of 108 patients with a one-to-one randomization. The Company plans to unblind the study approximately six months after the last patient was enrolled and report topline data in Q1 2015.
Solar cells are the future but for now they are resource-intensive, expensive and not very efficient - but the researchers in a new study can help with those first two. To make a solar cell, machines etch nanoscale spikes into a silicon wafer in order to maximize its surface area and the amount of sunlight that can reach it. Metal particles have been used as a catalyst in this process because etching is accelerated near metal particles. At first, gold was the metal of choice but that was never going to work in mass production so scientists found a way to switch to silver particles - much cheaper at around $20 per troy ounce but still not cost-effective enough for mass use, even in small amounts, when it comes to even a small, but typical for solar, 100MW facility.
Donald Spector is Chairman of New York College and just received Patent# 8,823,512 for a Wearable Biosensor, which he is donating to the college. The Wearable Biosensor patent predates the patents of the industry's leading technology companies, making it extremely valuable to a college, which can license it off to an Intellectual Property company that will get rich suing everyone. Why can he afford to do that?Because he has a lot more patents. He is the most prolific living inventor that most people could never identify by name.
A mutation in a gene called KNSTRN, which is involved in helping cells divide their DNA equally during cell division, is caused by ultraviolet light is likely the driving force behind millions of human skin cancers, according to new research.
Genes that cause cancer when mutated are known as oncogenes. Although KNSTRN hasn't been previously implicated as a cause of human cancers, the research suggests it may be one of the most commonly mutated oncogenes in the world.
A newly developed antifungal named isavuconazole is as effective as voriconazole against invasive mold disease in cancer patients with less adverse effects, according to phase 3 clinical data.
With age, our cells gradually lose their capacity to repair damage, even from normal wear and tear. A new paper discusses why this decline occurs in our skeletal muscle.
A team led by Dr. Michael Rudnicki, senior scientist at the Ottawa Hospital Research Institute and professor of medicine at the University of Ottawa, found that as muscle stem cells age, their reduced function is a result of a progressive increase in the activation of a specific signaling pathway. Such pathways transmit information to a cell from the surrounding tissue. The particular culprit identified by Dr. Rudnicki and his team is called the JAK/STAT signalling pathway.
The hygiene hypothesis and its cousins, like that rural settings make children microbiologically stronger, now has a study that vegetarian activists are not going to like: sleeping on animal fur in the first three months of life has been linked to reduced risk of asthma.
Previous studies have suggested that exposure to a wider range of environments from young age could be protective against asthma and allergies - urban settings have not found that to to be so. But in a new study, researchers investigated children from a city environment who had been exposed to animal skin by sleeping on the material shortly after birth.
In order to understand the genesis and treatment of cancer scientists are searching for links between genetic alterations and those diseases.
Historically, most of those studies have focused on the portion of the human genome that encodes protein – about 2 percent of human DNA overall. The vast majority of genomic alterations associated with cancer lie outside protein-coding genes, in what biologists call "junk DNA" and that colloquially became considered junk to the public, even though that is no more accurate than the Higgs boson being an actual God Particle. "Junk DNA" is anything useless rubbish – much of it is transcribed into RNA, for instance - but finding meaning in the sequences remains a challenge.
Materials made from nano-particles have long been touted as the future viable solar energy production and better touch screens.
The black box between the present and the future of these wonder-materials is organizing the nanoparticles into orderly arrangements. Nanoparticles of magnetite, the most abundant magnetic material on earth, are found in living organisms from bacteria to birds. Nanocrystals of magnetite self-assemble into fine compass needles in the organism that help it to navigate.
The number of California blue whales has rebounded to near historical levels - and they would be even higher if they didn't run into or get hit by commercial shipping.
Blue whales, nearly 100 feet in length and weighing 190 tons as adults, are the largest animals on earth. And they are the heaviest ever, weighing more than twice as much as the largest known dinosaur, the Argentinosaurus. As a species, they were considered hunted nearly to extinction but new international laws have put enforceable limits on catches of whales and blue whales seem to be the first to have recovered.
The coffee plant has a newly sequenced genome and that can tell scientists what they really want to know about: the evolution of caffeine.
The sequences and positions of genes in the coffee plant show that they evolved independently from genes with similar functions in tea and chocolate, which also make caffeine. Coffee did not inherit caffeine-linked genes from a common ancestor, but instead developed the genes on its own.
Why Coffee?
