Scientists have reported that an experimental vaccine targeting one of the most common genetic drivers of pancreatic cancer, called mutant KRAS, is safe and generated a durable immune responses aimed at preventing the cancer.
All across the world, there is one thing babies share in common; their size, if they are born to healthy, well-educated, well-nourished mothers.
The dose makes the poison, it is often said, and it is true. Lots of medicines and chemicals are harmless or beneficial in reasonable quantities but dangerous in high quantities. What about CO2 in plants? Plants need it for food but they also recognize too much is a bad thing.
Biologists have been studying a long-standing mystery concerning the way plants reduce the numbers of their breathing pores in response to rising carbon dioxide levels in the atmosphere.
The authors report the discovery of a new genetic pathway in plants, made up of four genes from three different gene families that control the density of breathing pores—or "stomata"—in plant leaves in response to elevated CO2 levels.
There are numerous ways to address carbon emissions but are we choosing the right approaches? America and Europe have invested heavily in subsidizing solar and wind generation and solar panels - but critics contend that the same money spent modernizing older buildings would have done far more than funding Chinese corporations or wealthy homeowners has.
Low-carbon energy won't cost more than what is currently spent on today's fossil-dominated energy system, according to new research from the International Institute for Applied Systems Analysis (IIASA) and partners.
Evolutionary adaptations have allowed Tibetans to have no trouble living at 13,000 feet, but how they became able to conquer the harsh environment of hypoxia has long been a mystery.
Medicine is advancing rapidly and it always has risks, but in early going the risks are going to be greater. A paper found that the risk of patient harm increased two-fold in 2006, the year when teaching hospitals nationwide embraced the pursuit of minimally invasive robotic surgery for prostate cancer.
What is the impact of volcanic sulfate emissions on climate? Researchers have completed the most accurate and precise reconstruction to date of historic volcanic sulfate emissions in the Southern Hemisphere, derived from a large number of individual ice cores collected at various locations across Antarctica and is the first annually resolved record extending through the Common Era - the last 2,000 years of human history.
Reconstructions of the past are critical to creating accurate model simulations used to assess natural versus anthropogenic climate forcing. Such model simulations underpin environmental policy decisions including those aimed at regulating greenhouse gas and aerosol emissions to mitigate projected global warming.
The small intestine is not easy to examine. X-rays, MRIs and ultrasound images provide snapshots but each suffers limitations.
The average human small intestine is roughly 23 feet long and 1 inch thick. Sandwiched between the stomach and large intestine, it is where much of the digestion and absorption of food takes place. It is also where symptoms of irritable bowel syndrome, celiac disease, Crohn's disease and other gastrointestinal illnesses occur. To assess the organ, doctors typically require patients to drink a thick, chalky liquid called barium. Doctors then use X-rays, magnetic resonance imaging and ultrasounds to assess the organ, but these techniques are limited with respect to safety, accessibility and lack of adequate contrast, respectively.
Lasers are ubiquitous but there are still wavelengths for which only large and expensive ones exist, or none at all. Remote sensing and medical applications call for compact laser systems, for example with wavelengths from the near infrared to the Terahertz region and now researchers at the Technische Universitaet Muenchen and the University of Texas Austin have developed a 400 nanometer thick nonlinear mirror that reflects frequency-doubled output using input light intensity as small as that of a laser pointer.
Recent meta-analyses of the efficacy of second-generation antidepressants for youth have concluded that they possess anadvantage over placebo in terms of clinician-rated depressive symptoms, but no meta-analysis has included measures of quality of life, global mental health, self-esteem, or autonomy. Prior meta-analyses also did not include self-reports of depressive symptoms.A recent article published in Psychotherapy and Psychosomatics reviewed the literature to understand the effects of antidepressant drugs on well-being in children and adolescents.
Fish is good for you and has been growing in popularity. Atlantic Bluefin Tuna is a much sought after delicacy, though the International Union for Conservation of Nature (IUCN) lists it as endangered. So far, farming of this species in the Mediterranean area involves capturing medium-sized specimens and fattening these in farms, which still depletes the wild stocks - but a sustainable solution may be available.
Skeletal remains uncovered near the site of a Roman villa in Dorset are likely the five skeletons of the owners and occupants of the villa – the first time in Britain that the graves of villa owners have been found in such close proximity to the villa itself.The five skeletons were two adult males, two adult females and an elderly female – with researchers postulating that they could be the remains of three generations of the same family, who all owned the villa. The bones are thought to date from the mid-4th Century (around 350 AD).
A new study addresses the relationship between personality and heart attacks. Distressed (type D) personality (TDP), characterized by high negative affectivity and social inhibition, along with depression, anxiety and other negative affects (such as demoralization, hopelessness, pessimism and rumination) have been implicated as potential risk factors for coronary artery disease. While some evidence suggests that the
negative affectivity
dimension of
Distressed (type D) personality
overlaps at least partially with depression, other studies underline how ‘TDP refers to a chronic, more covert form of distress that is distinct from depression'.
