Scientists have reported that an experimental vaccine targeting one of the most common genetic drivers of pancreatic cancer, called mutant KRAS, is safe and generated a durable immune responses aimed at preventing the cancer.
Pictured is Sydney Kandell with MSU and Sparrow Hospital residents Tiffany Burns and Lee Murphy just after surgery to remove the aggressive tumor that was causing her rare form of Cushing disease. Credit: Sydney Kandell
The symptoms of Cushing disease are unmistakable to those who suffer from it – excessive weight gain, acne, distinct colored stretch marks on the abdomen, thighs and armpits, and a lump, or fat deposit, on the back of the neck. Yet the disorder often goes misdiagnosed.
Biologists have long wondered if mammals share the elegant system used by insects, bacteria and other invertebrates to defend against viral infection. Two back-to-back studies in the journal Science last year said the answer is yes, but a study just published in Cell Reports by researchers at the Icahn School of Medicine at Mount Sinai found the opposite.
In the Mount Sinai study, the results found that the defense system used by invertebrates — RNA interferences or RNAi — is not used by mammals as some had argued. RNAi are small molecules that attach to molecular scissors used by invertebrates to cut up invading viruses.
You probably knew this but a new report in
Mayo Clinic Proceedings confirms that facial hair, sparks and home oxygen therapy can be dangerous.
Researchers reviewed home oxygen therapy-related burn cases and experimented with a mustachioed mannequin, a facial hair-free mannequin, nasal oxygen tubes and sparks. They found that facial hair raises the risk of home oxygen therapy-related burns, and encourage health care providers to counsel patients about the risk.
For obese people, food is a habit. They associate a movie with chips or cake and a movie is not a movie without the snack. Taken out of their routines, people quickly unlearn such habits.
Nothing overturns routine like pregnancy - and that may a great inroad to better health. Results presented this weekend at the joint meeting of the International Society of Endocrinology and the Endocrine Society (ICE/ENDO 2014 in Chicago) found that obese pregnant women who adhere to an intensive nutritional and exercise program starting in the first trimester gained less weight and had fewer pregnancy complications compared with peers who receive standard prenatal care.
6,000 years ago, farmers were truly organic - and the diseases that can bring were even more prevalent then. But prehistoric people can be absolved of any guilt, they had no way to know that agricultural irrigation systems could add to their disease burden.Researchers recently found what might be the oldest evidence of man-made technology inadvertently causing disease outbreaks, thanks to the discovery of a schistosomiasis parasite egg in a 6200-year-old grave at a prehistoric town by the Euphrates river in Syria.
The Brus, written by John Barbour, Archdeacon of Aberdeen, in about 1375, covers the Wars of Independence waged by Robert the Bruce, and includes a vivid, early description of the Battle of Bannockburn, which will have its 700th anniversary this week.It is one of the best-known works written in early Scots and its central theme - that freedom is a prize worth winning at all costs - has resonated in Scotland through the ages and is a poignant reminder before the Scottish Independence Referendum.
IAstronomers have discovered a bright, mysterious geologic object in
radar images of Ligeia Mare, the second-largest sea on Saturn's moon Titan.
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Scientifically speaking, this is a transient feature. They want to call it a magic island and so do we. Titan, the largest of Saturn's 62 known moons, is a world of lakes and seas. The moon – smaller than our own planet – bears close resemblance to watery Earth, with wind and rain driving the creation of strikingly familiar landscapes. Under its thick, hazy nitrogen-methane atmosphere, astronomers have found mountains, dunes and lakes. But in lieu of water, liquid methane and ethane flow through riverlike channels into seas the size of Earth's Great Lakes.
The Higgs boson was detected using its decay into bosons but scientists from the CMS experiment at the Large Hadron Collider have found evidence for the direct decay of the Higgs boson into fermions.
If the Higgs particle can decay into both bosons and fermions, we can exclude certain theories predicting that the Higgs particle does not couple to fermions. As a group of elementary particles, fermions form the matter while bosons act as force carriers between fermions.
Lung cancer causes more deaths in the U.S. than the next three most common cancers - colon, breast, and pancreatic - combined, for a simple reason: poor detection.
You can be living your life with no symptoms while it is metastasizing uncontrollably and it reaches the point of no return.
A research team has revealed conflicting climate change patterns between the middle latitude areas of the Northern and Southern Hemispheres in relation to glacial and interglacial cycles which have been a puzzle for the past 60 years.
Their study collected samples from the stalagmites and flowstones in limestone caves which are called 'hard disks' containing the past climate change data and revealed how much they grew in which eras through isotope analysis and age dating, and traced the past climate changes by applying them to global climate change over 550,000 years.
Anesthesia works, we know that. Properly done, patients can be temporarily rendered completely unresponsive during surgery and then wake up again, with their memories and skills intact. Improperly done, of course, can be very bad.
But little is understood about the processes used by structurally normal brains to navigate from unconsciousness back to consciousness. Anesthesia leads the world in retracted papers.
Previous research has shown that the anesthetized brain is not "silent" under surgical levels of anesthesia but experiences certain patterns of activity, and it spontaneously changes its activity patterns over time.
In a marked cemetery northwest of Lake Baikal, a skeleton was found, buried ceremoniously with a nephrite disk and four arrowheads, one of which was broken and found in the eye socket. An arrow in the eye? That's no accident.After radiocarbon dating and analysis, it was determined the individual was a 35-40 year-old male from the early Bronze Age, between 2406 and 1981 B.C.Unlike most hunter-gatherer societies of the Bronze Age, the people of the Baikal region of modern Siberia (Russia) respected their dead with formal graves. This particular specimen was so unique that bioarchaeologist Angela Lieverse traveled across the world just to bring it back to the Canadian Light Source synchrotron for examination.
