Scientists have reported that an experimental vaccine targeting one of the most common genetic drivers of pancreatic cancer, called mutant KRAS, is safe and generated a durable immune responses aimed at preventing the cancer.
The number of deaths involving commonly prescribed painkillers is far higher than the number of deaths by overdose from heroin and cocaine.
In fact, the deaths due to overdose of opiods - legal painkillers - is higher than cocaine and heroin combined, according to a new paper. In a first-of-its-kind review of existing research, the McGill team has put the spotlight on a major public health problem: the dramatic increase in deaths due to prescribed painkillers, which were involved in more than 16,000 deaths in 2010 in the U.S. alone. Currently, the US and Canada rank #1 and #2 in per capita opioid consumption.
It doesn't matter if you were a quarterback or a shortstop, past participation in competitive team sports made participants in a recent analysis winners in the competition for better jobs, according to a recent paper.
Writing in the Journal of Leadership & Organizational Studies,
Kevin M. Kniffin, postdoctoral research associate at Cornell University's Dyson School of Applied Economics and Management, and colleagues found that people who played a varsity high school sport were assumed to be more self-confident, have more self-respect, and demonstrate more leadership than people who took part in other extracurricular activities.
With the successful leveling off of CO2, a long-lasting greenhouse gas implicated for most global warming, due to a switch to natural gas, activists have been focusing on methane.
While some of the claims have been controversial and used decades old Soviet data to exaggerate the issue, we do know that about 20 percent of methane emissions are due to livestock. Most people and a better standard of living means more need for food. Ruminants, like sheep and cows, burp methane.
In Europe, the presence of toxic chemicals has been considered a localized problem affecting only a few bodies of water but a new paper says there are large scale ecological risks for several thousands of European aquatic systems. The culprit: toxic chemicals.
They say that chemical toxicity represents an ecological threat to almost half of all European bodies of water, and in approximately 15% of cases, the biota in freshwater systems may even be subject to acute mortality.
Mitochondria are cell organelles located within animal and human cells. They produce energy for the organism, possess their own genetic material - mitochondrial DNA (mtDNA) - and are transmitted exclusively by the mother.
Depending on their activity and tasks, different numbers of mitochondria are present in a cell - usually a few hundred to a thousand per body cell.
Decreased cognitive ability and autistic-like behaviors have been linked to disruption of the function of the Adenomatous Polyposis Coli (APC) gene by Tufts researchers who deleted the gene from select neurons in the developing mouse brain.
The mice showed reduced social behavior, increased repetitive behavior, and impaired learning and memory formation, similar to behaviors seen in individuals with autism and intellectual disabilities. The authors say this study is the first to evaluate how the loss of APC from nerve cells in the forebrain affects brain development, learning, and behavior. The research team, led by Michele Jacob, Ph.D., engineered a new mouse model for studying cognitive and autistic-like disabilities.
A new study has found that the eye's optical quality deteriorates after alcohol consumption. Not just how the images are interpreted, the way some unemployed guy who is 'getting his band together' looks more attractive at 2 AM after a few shots of Jägermeister, but the physical eye itself.The authors say ethanol in the tear-film is one of the causes: it covers the surface of the eye, disturbs the outer layer and favors evaporation of the aqueous content of the tear, deteriorating the optical quality of the image we see. The deterioration in vision is significantly greater in subjects with breath alcohol content over the legal limit for driving, which is another obvious reason to call Uber and not drive yourself.
While probiotics don't do much of anything except make companies rich, fecal microbiota transplantation --- the process of delivering stool bacteria from a healthy donor to a patient suffering from intestinal infection with the bacterium Clostridium difficile --- has been shown to work by restoring healthy bacteria and functioning to the recipient's gut, according to a new study.
Harrisvaccines has been granted United States Department of Agriculture (USDA) conditional licensure of the company's Porcine Epidemic Diarrhea Virus (PEDv) Vaccine. PEDv is a highly contagious swine disease that entered the United States in April 2013. PEDv causes vomiting and diarrhea in older animals and extreme dehydration and mortality of up to 100 percent in piglets that are less than one week of age. Since entering the U.S. a year ago, PEDv has spread to nearly 30 states and throughout North America, causing the death of millions of piglets. PEDv is not a zoonotic disease, and therefore cannot spread to humans, but it has cost the pork industry and consumers hundreds of millions of dollars.
Amgen announced that it will collaborate with the National Cancer Institute and other public and private sector partners on the Lung Master Protocol (Lung-MAP), a clinical trial program that will use biomarker-driven research and genomic profiling to match squamous cell lung cancer patients to investigational treatments based on their individual cancer profiles.
Wind energy advocates were pressing Ohio Governor John Kasich to use his line-item veto to remove what they called an anti-wind-energy provision from a tax-cutting budget bill – a requirement that new installations be built further away from property lines.Critics of wind energy believe wind turbines nearby cause headaches, insomnia and other maladies. Environmental groups and wind energy corporations dismiss the claims as anecdotal evidence. The budget bill bring $400 million in tax cuts.
For decades, the conventional medical wisdom has been the lower the better for blood pressure, with 120/80 being the goal and even lower if possible. But does that approach result in reduced risk for dangerous heart events for the approximately one in three people in this country who have high blood pressure?
Perhaps not, according to an article in JAMA Internal Medicine, where researchers at Wake Forest Baptist Medical Center found that lowering systolic blood pressure below 120 does not appear to provide additional benefit for patients. Systolic pressure is the top number in a standard blood pressure reading (e.g., 120/80).
