Many of the areas of the human genome previously thought to be deserts are in fact teeming with life.

Most known human genes in the genome map are still incompletely annotated, says Professor Alexandre Reymond, from the Centre for Integrative Genomics, University of Lausanne, Switzerland and the Department of Genetic Medicine, University of Geneva, Geneva, Switzerland.

“We found that the vast majority of the protein coding genes we studied utilised often in a tissue-specific manner previously unknown set of exons [the regions of DNA within a gene that are transcribed to messenger RNA] outside the current boundaries of the annotated genes ”, according to Professor Reymond.

Researchers at Rensselaer Polytechnic Institute and the University of Akron have created synthetic “gecko tape” with four times the sticking power of the real thing.

The researchers describe a process for making polymer surfaces covered with carbon nanotube hairs. The nanotubes imitate the thousands of microscopic hairs on a gecko’s footpad, which form weak bonds with whatever surface the creature touches, allowing it to “unstick” itself simply by shifting its foot.

For the first time, the team has developed a prototype flexible patch that can stick and unstick repeatedly with properties better than the natural gecko foot. They fashioned their material into an adhesive tape that can be used on a wide variety of surfaces, including Teflon.

How social or altruistic behavior evolved has been a central and hotly debated question, particularly by those researchers engaged in the study of social insect societies of ants, bees and wasps.

After the tremendous discoveries in basic biology of the last 100 years, you might think that we would understand by now what a gene is. But the big news in genome biology this week is the publication of the results of the ENCODE project, a large scale experimental (as opposed to just computational) survey of the human genome. The leaders of the ENCODE project suggest that we need to, yet again, rethink just what exactly a gene is.

Parkinson disease (PD) is a common neurodegenerative disease characterized by the selective loss of midbrain dopaminergic neurons.

Although the cause of PD is unknown, pathological analyses have suggested the involvement of oxidative stress and mitochondrial dysfunction. Recently, an inherited form of early-onset PD has been linked to mutations in both copies of the gene encoding the mitochondrial protein PINK1. Furthermore, increasing evidence indicates that single-copy mutations in PINK1 are a significant risk factor in the development of later-onset PD.

With a technology transfer agreement announced today, the first compact proton therapy system – one that would fit in any major cancer center and cost a fifth as much as a full-scale machine – is one step closer to reality.

Proton therapy is considered the most advanced form of radiation therapy available, but size and cost have limited the technology’s use to only six cancer centers nationwide.

Compact proton radiotherapy treatment concept
Illustration by Steven Hawkins

A team of LLNL researchers has conceptually proven that a three-in-one machine, or “universal point detection system,” that can detect explosive, chemical and biological agents all at the same time, can be achieved, said George Farquar, a postdoctoral fellow and physical chemist at the LLNL’s Glenn T. Seaborg Institute.

Audrey Martin adjusts the lens stack of SPAMS. Martin, who worked at LLNL for 15 weeks last summer as a Department of Homeland Security (DHS) Fellow, is the first DHS intern hired into the Laboratory as a full-time student employee.

At some level, all types of matter that we usually deal with have at least one thing in common - they're made of particles. The solids, liquids, gases and plasmas that surround us are built of atoms, which are made of electrons, protons and neutrons. Protons and neutrons in turn are made of quarks.

According to Harvard University's Howard Georgi, however, there's at least the theoretical possibility that some matter in the universe is not made of particles at all. Georgi has dubbed the mind-bending matter "unparticle stuff," and hopes that we may see signs of it at the Large Hadron Collider (LHC), a super high energy proton collider due to come online in Europe later this year.

Alan Hubert and Dixie Dansercoer collect snow-depth data for ESA's CryoSat-2 mission. They're seasoned polar explorers so they are used to dealing with physically demanding and downright harsh conditions but what they encountered during their three and a half-month expedition from Russia to Greenland via the North Pole was dangerous even for them.

They didn't expect that the Lincoln Sea in the Arctic Ocean, the very ice they were on, would begin to disintegrate. Aside from the dangerous conditions they also had to circumnavigate the ice-free water leads.

Scientists at University College Cork have discovered that probiotic bacteria can protect against bacterial infection. The work was carried out in the Alimentary Pharmabiotic Centre (APC) in UCC.

The APC, funded by Science Foundation Ireland, was set up investigate the beneficial roles of the bacteria found in the gastro-intestine of healthy humans.

The research group examined a range of beneficial bacteria and found one specific probiotic bacterium (Lactobacillus salivarius UCC118) which was able to kill Listeria monocytogenes, an often lethal pathogen in pregnant women. The probiotic kills the pathogen by producing an antibiotic-like compound called a bacteriocin.