Hari Jayaram just listed my blog as one that makes him think. Keeping the meme going, I'll list 5 that have had an impact on me. 1. Beth's Second Life Beth Ritter-Guth has been a huge inspiration for me and she is the main reason I pulled the trigger on getting involved with Second Life for my teaching and research. We have collaborated on many other projects involving social software and new approaches to education - Google her name for many more goodies. 2. Chem-bla-ics Egon Willighagen has been instrumental to the cheminformatics community.

By giving ordinary adult mice a drug - a synthetic designed to mimic fat - Salk Institute scientist Dr. Ronald M. Evans is now able to chemically switch on PPAR-d, the master regulator that controls the ability of cells to burn fat. Even when the mice are not active, turning on the chemical switch activates the same fat-burning process that occurs during exercise. The resulting shift in energy balance (calories in, calories burned) makes the mice resistant to weight gain on a high fat diet.

Northwestern University scientist Mary J.C. Hendrix and colleagues discovered that aggressive melanoma cells (but not normal skin cells nor less aggressive melanoma cells) contain specific proteins similar to those found in embryonic stem cells. This groundbreaking work led to the first molecular classification of malignant melanoma and may help to explain how, by becoming more like unspecialized stem cells, the aggressive melanoma cell gained enhanced abilities to migrate, invade and metastasize while virtually undetected by the immune system.

A new study from the University of Michigan Health System suggests that a compound in green tea may provide therapeutic benefits to people with rheumatoid arthritis.

The study looks at a potent anti-inflammatory compound derived from green tea. Researchers found that the compound -- called epigallocatechin-3-gallate (EGCG) -- inhibited the production of several molecules in the immune system that contribute to inflammation and joint damage in people with rheumatoid arthritis.

Lately they've been dropping like flies—Imus, Rosie, Rumsie. Who's next? Gonzales? Wolfowitz? And then there's Alec Baldwin—he doesn't, technically, have anything to resign from, but what are the chances his career can recover from the temper tantrum he left on his 12-year old daughter's phone? What about a more esoteric resignation candidate like Cheney? Is there any hope?

“The climate problem can by and large be solved if the eight to ten largest countries in the world can agree on effective climate measures,” says Professor Jon Hovi.

One of the themes at a recent climate conference arranged by the research program RENERGI was how we can achieve an effective international climate agreement. Professor in political science Jon Hovi at the University of Oslo and CICERO has studied this topic for years. He argues that although the international community faces many obstacles in mitigating the climate problem, solutions are possible.

Continue the Kyoto Process?

Hopkins researchers have identified a backup supply of stem cells that can repair the most severe damage to the nerves responsible for our sense of smell. These reservists normally lie around and do nothing, but when neighboring cells die, the scientists say, the stem cells jump into action.

Mice whose brains had lost a large number of neurons due to neurodegeneration regained long-term memories and the ability to learn after their surroundings were enriched with toys and other sensory stimuli, according to new studies by Howard Hughes Medical Institute researchers. The scientists were able to achieve the same results when they treated the mice with a specific type of drug that encourages neuronal growth.

Life for an estimated 100,000 people in poverty-stricken rural India has been improved dramatically by several hours of reliable solar-powered lighting every night, made available by a UN-led pilot project to facilitate household financing for solar home systems.

The $1.5 million pilot, managed by the United Nations Environment Programme (UNEP), has improved so many lives in India that sister programmes to boost energy access are being initiated in other developing countries.

US and Mexican conservation efforts may have boosted the number of marine turtles visiting UK waters, according to University of Exeter biologists.

New research by the University of Exeter and Marine Environmental Monitoring, published this week in Marine Biology (3 May 2007), analyses 100 years of data. It shows an increase in the number of loggerhead and Kemp’s ridley turtles in UK and French waters in the last twenty years. The research team believes this is most likely the result of protective measures put in place in the United States and Mexico.