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What Next For Messenger RNA (mRNA)? Maybe Inhalable Vaccines

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The mosquito transmitted Chikungunya virus, which causes Chikungunya fever, is spreading continuously. No vaccine is so far available. Researchers of the Paul-Ehrlich-Institut have experimentally recombined segments of the virus surface protein E2, thus creating artificial proteins. The domain generated that way - "sAB+" - was able to confer a protective effect against Chikungunya virus to the animal. An immunization by means of this small protein fragment could thus provide a suitable approach to developing a Chikungunya vaccine.

Dropping off a child at kindergarten for the first time can be one of the most memorable yet terrifying experiences of parenthood. Among the many concerns parents face is the worry whether your child will make friends - a key factor, research shows, in reducing anxiety, depression and the likelihood of being bullied.

For parents of children with disabilities, the concern is even greater as four-out-of-10 of their children will enter kindergarten without the social skills necessary to develop close friendships. The response from schools has been to create inclusive classrooms, where a significant number of students with disabilities now receive the majority of their education and are believed to have a better chance at developing close relationships with peers.

Scientists have discovered that neurons use minor "DNA surgeries" to toggle their activity levels all day, every day, and since these activity levels are important in learning, memory and brain disorders, it could shed light on a range of important questions. 

"We used to think that once a cell reaches full maturation, its DNA is totally stable, including the molecular tags attached to it to control its genes and maintain the cell's identity," says Hongjun Song, Ph.D., a professor of neurology and neuroscience in the Johns Hopkins University School of Medicine's Institute for Cell Engineering. "This research shows that some cells actually alter their DNA all the time, just to perform everyday functions."

Bees play an invaluable role in maintaining biodiversity and in pollinating the crops that feed the world, so it is essential to improve our understanding of their biology and to investigate how they respond to environmental threats. Despite their often slow and apparently bumbling flights from flower to flower, bumblebees are anything but lazy. With over 250 bumblebee species globally, these important insects perform the laborious task of pollinating flowers in both wild and agricultural settings. A large number of fruits and vegetables would be missing from our plates had a bumblebee not done its job. 

Researchers gave bumblebees the option to choose between a sugar solution with nicotine in it and one without and found that bees infected with the Crithidia bombi parasite were more likely to go for the nicotine-laced nectar than those that weren't infected.

Happy Meals for broccoli?

A paper presented at the Pediatric Academic Societies (PAS) annual meeting in San Diego says that because poor food choices in school cafeterias are a risk factor for childhood obesity, students will make better choices if healthy foods are labeled with smiley faces and have prizes - similar to what fast food corporations do to try and make lunch more fun.