The therapeutic promise of human stem cells is indisputably huge, but the process of translating their potential into effective, real-world treatments involves deciphering and resolving a host of daunting complexities.

Writing in the February 25 online issue of the journal PLOS ONE, researchers at University of California, San Diego School of Medicine, with collaborators from The Scripps Research Institute (TSRI), have definitively shown for the first time that the culture conditions in which stem cells are grown and mass-produced can affect their genetic stability.

The activity of the Sun is an important factor in the complex interactions that control our climate. We don't really even understand the impacr of the sun - it is not constant over time, but has greater significance when the Earth is cooler, according to a new paper in Geology.

There has been discussion as to whether variations in the strength of the Sun have played a role in triggering climate change in the past, but more and more research results clearly indicate that solar activity - i.e. the amount of radiation coming from the Sun - has an impact on how the climate varies over time.

Not all storks migrate to Africa, many spend the winter in the Iberian Peninsula, where landfills have become a permanent source of food. Scientists from Extremadura have analyzed the presence of pollutants and pesticides (some prohibited in Spain) in the blood of nestlings from three colonies, two of which are close to landfill sites, and the results reveal that the main source of contamination can be due to the use of insecticides still used in African countries where the birds migrate to, who transfer their contaminated load onto their offspring through their eggs.

The U.S. and other countries are enacting rules to clamp down on the sales of fake pharmaceuticals, which pose a public health threat. But figuring out a system to track and authenticate legitimate drugs still faces significant obstacles, according to an article in Chemical & Engineering News (C&EN), the weekly newsmagazine of the American Chemical Society.

Under normal conditions, many of the different types of tissue-specific adult stem cells, including hematopoietic stem cells, exist in a state or dormancy where they rarely divide and have very low energy demands. "Our theory was that this state of dormancy protected hematopoietic stem cells from DNA damage and therefore protects them from premature aging," says Dr. Michael Milsom, leader of the study.

The push to boost food production in East Africa that is accelerating the conversion of natural lands into croplands may be significantly increasing the risk of plague according to a new study in the American Journal of Tropical Medicine and Hygiene.