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Paths To Autism: One Or Many?

Paths To Autism: One Or Many?

Philadelphia, PA, July 19, 2016 - A new report in Biological Psychiatry reports that brain alterations in infants at risk for autism may be widespread and affect multiple systems, in contrast to the widely held assumption of impairment specifically in social brain networks.
Autism is diagnosed based on impairments in social and communication behaviors. These symptoms tend to emerge in the second year of life, but identifying abnormalities in early infancy could help researchers understand how autism develops and potentially allow clinicians to predict the disorder before it emerges.

Prostate Cancer: Should Screening Test Procedures Be Tightened Again?

Prostate Cancer: Should Screening Test Procedures Be Tightened Again?

The number of new cases of men suffering from metastatic prostate cancer has risen significantly in a decade's time, and is 72 percent greater in the year 2013 compared to 2004. This increase is especially worrying among men aged between 55 and 69 years old - the age group thought to benefit most from prostate cancer screening and early definitive treatment. These are some of the findings of a study published in Springer Nature's journal Prostate Cancer and Prostatic Diseases. According to authors Adam Weiner and Edward Schaeffer of Northwestern University Feinberg School of Medicine in the US, the research highlights a continued need to refine prostate cancer screening and treatment in the United States.

How Meltwater From The Ice Sheets Disturbed The Climate 10,000 Years Ago

How Meltwater From The Ice Sheets Disturbed The Climate 10,000 Years Ago

Today, a negative correlation is observed in the amount of rainfall in north-western Africa and north-western Europe. If a humid winter climate prevails in north-western Europe, the climate in north-western Africa is dry. Due to melting ice sheets, this correlation was reversed in the early Holocene period; this resulted in both regions being humid respectively dry at the same time. Radical climate change occurred. The researchers have published their report in the current edition of Nature Geoscience.
Climate determined by opposing atmospheric pressures

What Are Gut Bacteria Doing In Critically Ill Lungs?

What Are Gut Bacteria Doing In Critically Ill Lungs?

No one knows for sure how they got there. But the discovery that bacteria that normally live in the gut can be detected in the lungs of critically ill people and animals could mean a lot for intensive care patients. 
Today, scientists are reporting that they found gut bacteria in the deepest reaches of failing lungs -- an environment where they normally aren't found and can't survive. The more severe the patients' critical illness, the more their usual lung bacteria were outnumbered by the misplaced gut bugs.

How To Decide If Watchful Waiting Is The Right Choice

How To Decide If Watchful Waiting Is The Right Choice

(PHILADELPHIA) - Over 90 percent of prostate cancers are detected at a curable stage, with men more likely to die of other diseases than from this cancer. Although patients with localized, low-risk prostate cancer have treatment options: active surveillance, also called watchful waiting, in which the cancer is monitored periodically to detect any changes, or active treatment with surgery and radiation. This choice is challenging, because medical science cannot reliably identify those men who are at risk for developing aggressive disease and may benefit from active treatment. Nonetheless, most men diagnosed with localized, low-risk prostate cancer choose active treatment.

Middle School Students Use 3-D Printing To Help Disabled Penguin Walk Again

Middle School Students Use 3-D Printing To Help Disabled Penguin Walk Again

A disabled African penguin at Mystic Aquarium in Mystic, Connecticut has gotten a new boot, thanks to 3-D printing and some middle school students. Yellow/Purple (AKA “Purps”), a resident of Mystic Aquarium’s endangered African penguin colony,  was left with a nonfunctional flexor tendon in her ankle following a fight with another penguin. In an initial effort to immobilize, support and protect the site of injury, veterinarians at Mystic Aquarium fashioned a boot for Purps from moldable plastic material. While adequate, the animal care team at Mystic Aquarium knew there were more modern solutions available for the boot that would not only be more durable and less cumbersome for the small bird, but also would require less time than handcrafting a boot.

Environmentalists In Academia Link Increased Risk Of Asthma Attacks To Natural Gas Wells

Environmentalists In Academia Link Increased Risk Of Asthma Attacks To Natural Gas Wells

Johns Hopkins Bloomberg School of Public Health  graduate student Sara G. Rasmussen, from their Department of Environmental Health Sciences, says that people with asthma who live near bigger or larger numbers of active hydraulic fracturing (fracking) natural gas wells are 1.5 to four times likelier to have asthma attacks than those who live farther away.

Dual Antigen Targeting May Improve CAR T Cell Cancer Therapy

Dual Antigen Targeting May Improve CAR T Cell Cancer Therapy

Chimeric antigen receptor T cells (CAR T cells) are a promising immunotherapy approach to cancer treatment in which a patient's own immune cells attack tumors by targeting an identifying marker, or antigen, that is displayed at high levels on cancerous cells. However, CAR T cells that target a single antigen have had mixed results in clinical trials, which may be due to ongoing variability in the antigens that tumors display. In this month's issue of the JCI, a team led by Nabil Ahmed at Baylor College of Medicine demonstrated that CAR T cells that were engineered to target two different tumor antigens were more effective at controlling tumors in an animal model than typical CAR T cells, which target a single antigen.

To Stop E-cigarette Use In Teens, You Need To Stop Rebellion In Teens

To Stop E-cigarette Use In Teens, You Need To Stop Rebellion In Teens

The U.S. Centers for Disease Control and Prevention have recently become concerned about e-cigarette use yet scarcely mention that cigarette uptake has plummeted.
Cigarettes are the killer, not nicotine, but nicotine is what historically turned smoking into what the American Council on Science and Health (ACSH) deems a pediatric disease. Like caffeine, nicotine is addictive. If you smoked caffeine in a cigarette, it would be incredibly toxic whereas nicotine itself is relatively harmless. And because the CDC has overreacted to e-cigarettes, they become a cool rebellious thing for teems, just like cigarettes once were.

City Birds Again Prove To Be Angrier Than Rural Birds

City Birds Again Prove To Be Angrier Than Rural Birds

No need to head to the movie theater or download the video game app: Angry Birds can be found right in your backyard this summer--if you live in the suburbs, that is.
Virginia Tech researchers recently found that birds that live in suburban areas exhibit significantly higher levels of territorial aggression than their country counterparts. The results were recently published in Biology Letters.

Butterflies' Diet Impacts Evolution Of Traits

Butterflies' Diet Impacts Evolution Of Traits

Why do some organisms within a single species have many offspring, while others have relatively few? A new study led by University of Minnesota researcher Emilie Snell-Rood finds that access to some nutrients may be a star player in shaping traits related to fitness such as fecundity and eye size over the long term. Given drastic increases in the availability of many nutrients due to the widespread use of fertilizers and road salts, the finding has important implications for agriculture and ecology.

Defining What It Means To Be A Naive Stem Cell

Defining What It Means To Be A Naive Stem Cell

Whitehead Institute scientists have created a checklist that defines the "naive" state of cultured human embryonic stem cells (hESCs). Such cells can mature into almost any cell type and more closely resemble the unique molecular features of pluripotent cells in the early human embryo than adult stem cells. Since the late 1990s, scientists have been very interested in working with naive stem cells, but they have been more hope than promise; they don't even have a common definition of what makes a cell truly naive.