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What Next For Messenger RNA (mRNA)? Maybe Inhalable Vaccines

No one likes getting a needle but most want a vaccine. A new paper shows progress for messenger...

Toward A Single Dose Smallpox And Mpox Vaccine With No Side Effects

Attorney Robert F. Kennedy Jr. and his US followers over the last 25 years have staunchly opposed...

ChatGPT Is Cheaper In Medicine And Does Better Diagnoses Even Than Doctors Using ChatGPT

General medicine, routine visits and such, have gradually gone from M.D.s to including Osteopaths...

Even After Getting Cancer, Quitting Cigarettes Leads To Greater Longevity

Cigarettes are the top lifestyle risk factor for getting cancer, though alcohol and obesity have...

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Cockroaches have a reputation for resilience, likely contributing to the belief that they could even survive a nuclear bomb and subsequent radiation exposure.

And though Fukushima was not a nuclear bomb, or even a real disaster (more people died trying to escape than from radiation), the claim that cockroaches were found led weight to their constitutions.(a) But is it really accurate? In the future, if a disgraced doctor finds Alita: Battle Angel in a junk pile, will she be with a cockroach? 

In vitro, in utero, these are science terms that have become commonly known. In vitro means studies in cells, like using test tubes, or a test for a fetus in the womb in the case of in utero.

Studies done in feces - yes, excrement - haven't really had a name, they though are common in gut bacteria analyses. Now they might, thanks to UNC School of Medicine scientist Aadra Bhatt, PhD, and colleagues; in fimo. Their proposal is published in the journal Gastroenterology.

An immune checkpoint molecule, SA-4-1BB developed for cancer immunotherapy also protects against future development of multiple types of cancer when administered by itself, shows a new study.

The recombinant protein molecule SA-4-1BBL has been used to enhance the therapeutic efficacy of cancer vaccines with success in pre-clinical animal models. It accomplishes this by boosting the effectiveness of CD8+ T cells, adaptive immune cells trained to target the tumor for destruction. When the researchers treated normal healthy mice with SA-4-1BBL alone, the mice were protected when the researchers later exposed them to different types of tumor cells.

Patrolling the body instead of generating an immune response after the tumor is present

Cellular barcoding has been used to tag, track and pinpoint cells responsible for the spread of breast cancer from the main tumor into the blood and other organs, and also revealed how chemotherapy temporarily shrinks the number of harmful cells, rather than eliminating them, explaining how the cancer could eventually relapse.

Pinpointing the 'seeders' of disease

Most deaths from breast cancer are caused by the metastasis, or spread, of cancerous cells from the main tumor site into other organs. 

Exposure to glyphosate — at 45 years of age the world’s most widely used, broad-spectrum herbicide and the primary ingredient in the weedkiller Roundup — increases the risk of some cancers by more than 40 percent, according to a meta-analysis published in the online journal Mutation Research/Reviews in Mutation Research, an imprint of publishing giant Elsevier.
Raw milk sold by Miller’s Biodiversity Farm in Quarryville, Pennsylvania and laced with Brucella strain RB51 has been linked to exposures in 19 states by the U.S. Centers for Disease Control and Prevention.

Raw milk, a recent trend by organic food lovers, lacks pasteurization, a process created by Louis Pasteur that has saved millions of lives by removing harmful bacteria like RB51. A cow that tested positive for RB51 has been removed from the milking herd and after one case of infection was confirmed in New York in November 2018, there are concerns that an unknown number of people may have been infected due to the milk from this farm.