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ADHD and driving - is the medicine worse than the problem?

ADHD and driving - is the medicine worse than the problem?

As a group, young ADHD drivers are two to four times more likely to have a car accident than non-ADHD drivers. Daniel Cox, Ph.D., professor of psychiatry and neurosciences at the University of Virginia Health System, has conducted research aimed at improving those odds. His team's newest study will look at the effects of methylphenidate (MPH), a controlled-release stimulant, on young ADHD drivers facing real-life distractions.

A diagnostic test for celebral malaria

A diagnostic test for celebral malaria

Scientists at CNRS and the Pasteur Institute, collaborating with physicians in Gabon, have just undertaken a study on cerebral malaria in children living in an endemic region. This study, which was published in PLoS ONE, should allow us to better understand this severe form of malaria which affects 20 to 40 percent of people infected by the Plasmodium falciparum parasite, and is fatal in 30 to 50 percent of cases. The study also provides a lead on how to perfect a diagnostic test, which should allow for better patient care.

Vaccine prevents Mad Mice Disease

Vaccine prevents Mad Mice Disease

An oral vaccine can prevent mice from developing Prion disease. Prion diseases, which include scrapie, mad cow disease, and chronic wasting disease, are fatal and there is no treatment or cure.
The disease spreads when an animal eats the body parts of other animals contaminated with prions. The disease causes dementia and abnormal limb movements.

A new view of photosynthesis

A new view of photosynthesis

Plants scavenge nearly every photon of available light energy to produce food. Yet after many years of careful research into its exact mechanisms, some key questions remain about this fundamental biological process that supports all life on earth.

The structure of the L and M subunits of the photosynthetic reaction center from Rhodobacter sphaeroides (based on PDB entry 1PCR). The protein is represented in purple, the cofactors are represented in red, blue, black and yellow. Credit: Professor Neal Woodbury, Biodesign Institute at ASU

Valproate users during pregnancy have children with lower IQs

Valproate users during pregnancy have children with lower IQs

Children of women who took the epilepsy drug valproate during pregnancy appear to be at a greater risk for lower IQ, according to research presented at the American Academy of Neurology's 59th Annual Meeting in Boston, April 28 – May 5, 2007.
The study looked at IQ results for 187 two-year-old children of mothers who took the epilepsy drugs carbamazepine, lamotrigine, phenytoin, or valproate during pregnancy.

Sirtuins - on the road to a vitamin for longevity

Sirtuins - on the road to a vitamin for longevity

Imagine taking a vitamin for longevity! Not yet, but a Dartmouth discovery that a cousin of niacin prolongs lifespan in yeast brings the tantalizing possibility a step closer.
The research, reported in the May 4 issue of Cell, shows how a new vitamin extends lifespan in yeast cells, much like calorie restriction does in animals. It could pave the way for developing supplements to benefit humans.

Study finds alcohol marketing associated with adolescent drinking

Study finds alcohol marketing associated with adolescent drinking

Children's exposure to alcohol advertising during early adolescence appears to influence both beer drinking and their intentions to drink a year later, according to a RAND Corporation study issued today.
The study of children in the sixth and seventh grades found that those exposed to alcohol advertising at high levels – from television, magazines, in-store displays and promotional items like T-shirts and posters – were 50 percent more likely to drink and 36 percent more likely to intend to drink than children whose exposure to alcohol advertising was very low.

The mechanics of asymmetric cell division

The mechanics of asymmetric cell division

When a cell divides, normally the result is two identical daughter cells. In some cases however, cell division leads to two cells with different properties. This is called asymmetric cell division and plays an important role in embryonic development and the self-renewal of stem cells. Researchers from the European Molecular Biology Laboratory (EMBL) have now worked out the mechanism underlying asymmetric cell division in nematode worms. The study, which is published in the current issue of Cell, reveals that interactions between the mitotic spindle and the cell cortex are crucial for asymmetric division.

Keeping your immune system from fighting food

Keeping your immune system from fighting food

After every meal, the body must prevent the immune system from launching an all-out fight against food. Now, researchers report the identity of a nutrient "floodgate" that serves to protect against such an inflammatory immune response.
The researchers found that animals lacking a protein enriched in fat cells, called STAMP2, develop acute inflammation in deep pockets of visceral fat. The animals also showed symptoms of metabolic syndrome—including insulin resistance and fatty liver disease—even while eating a regular diet.

IBM copies nature to build chips

IBM copies nature to build chips

IBM today announced the first-ever application of a breakthrough self-assembling nanotechnology to conventional chip manufacturing, borrowing a process from nature to build the next generation computer chips.
The natural pattern-creating process that forms seashells, snowflakes, and enamel on teeth has been harnessed by IBM to form trillions of holes to create insulating vacuums around the miles of nano-scale wires packed next to each other inside each computer chip.

Mercury has molten core

Mercury has molten core

Chefs have long used a simple trick to differentiate between a raw and hard-boiled egg. By spinning an egg and watching how it behaves when the spin is disrupted, it's easy to tell whether its interior is solid or liquid.
Applying a similar test to the planet Mercury, astronomers have found strong evidence that the planet closest to the sun has a fluid core. The research, led by Jean-Luc Margot, assistant professor of astronomy at Cornell, appears this week on the Web site of the journal Science.

Reducing protein tau can prevent neurological deficits related to Alzheimer's

Reducing protein tau can prevent neurological deficits related to Alzheimer's

Scientists at the Gladstone Institute of Neurological Disease (GIND) have discovered that reducing levels of the protein tau can prevent seizures and neurological deficits related to Alzheimer's disease. The findings, reported today in the journal Science, demonstrate that when tau is removed from mice genetically engineered to simulate Alzheimer's disease, their memory function is retained and they live a normal lifespan. Reducing tau levels also made mice more resistant to epileptic seizures.