News Articles

Crohn’s disease is a chronic relapsing inflammatory disorder of the intestinal tract that affects an estimated 0.15% of people in the developed world. Common symptoms include abdominal pain and diarrhea, but the disorder is often associated with debilitating clinical complications. Researchers from the University of Liège, Belgium, have now uncovered an important clue to the susceptibility of individuals to this disease.

Scientists have discovered one of the reasons why bladder cancer is so much more prevalent in men than women: A molecular receptor or protein that is much more active in men than women plays a role in the development of the disease. The finding could open the door to new types of treatment with the disease.
In an article in the April 4 issue of the Journal of the National Cancer Institute, Chawnshang Chang, Ph.D., of the University of Rochester Medical Center and colleagues show that the androgen receptor, which is central to the action of testosterone and other hormones that are much more plentiful in men than women, appears to play a key role in the disease.

Serotonin is a major signaling chemical in the brain, and it has long been thought to be involved in aggressive behavior in a wide variety of animals as well as in humans. Another brain chemical signal, neuropeptide Y (known as neuropeptide F in invertebrates), is also known to affect an array of behaviors in many species, including territoriality in mice. A new study by Drs. Herman Dierick and Ralph Greenspan of The Neurosciences Institute in San Diego shows that these two chemicals also regulate aggression in the fruit fly, Drosophila melanogaster.

A new study says targeting smaller (¡Ü5 mm) lesions does little to significantly reduce the incidence of colorectal cancer (CRC) and, in fact, results in extremely high financial costs and a large proportion of adverse events. Published in the June 1, 2007 issue of CANCER, a peer-reviewed journal of the American Cancer Society, a cost-benefit analysis study says the low malignancy rate among so-called diminutive polyps gives virtual colonoscopy with removal of lesions 6 mm or greater the best estimated value per life year gained and with fewer complications.

Mayo Clinic researchers, along with collaborators from the National Institutes of Health (NIH) and University of Oslo, Norway, have discovered that a miscue of the body’s genetic repair system may cause Huntington’s disease, a fatal condition that affects 30,000 Americans annually by destroying their nervous system. Until now, no one knew how Huntington’s begins, only that it is incurable. The findings appear in the online issue of the journal Nature.

The most recent census of mountain gorillas in Uganda’s Bwindi Impenetrable National Park—one of only two places in the world where the rare gorillas exist—has found that the population has increased by 6 percent since the last census in 2002, according to the Uganda Wildlife Authority, the Wildlife Conservation Society, the Max Planck Institute of Anthropology and other groups that participated in the effort.

Adolescents who are chronically exposed to family turmoil, violence, noise, poor housing or other chronic risk factors show more stress-induced physiological strain on their organs and tissues than other young people.
However, when they have responsive, supportive mothers, they do not experience these negative physiological changes, reports a new study from Cornell.

Runners in today's London Marathon may be tempted to down several litres of water to keep their cool and achieve their best time, but large fluid intake does not achieve either, according to a sports scientist from the University of Exeter.
With today's temperatures expected to reach 19 degrees, the average runner will potentially lose almost a litre of sweat every hour and reach a body temperature of over 39 degrees, two degrees above normal. The sporting community has long assumed that drinking large amounts of water helps to keep the body's temperature down, which improves performance. A recent study led by Dr Chris Byrne of the University of Exeter shows that the level of fluid intake has absolutely no effect on body temperature or performance.

Scientists are questioning whether peer review, the internationally accepted form of scientific critique, is able to meet the challenges posed by the rapid changes in the research landscape. A report published by the European Science Foundation (ESF) has showcased a number of options that could lead to a greater openness to innovative research.
The report "Peer review: its present and future states", which draws on ideas from an international conference in Prague in October 2006, reflects some concern on the shortcomings of peer review while outlines some possible measures to cope with them.

Warm gas escaping from the clutches of enormous black holes could be the key to a form of intergalactic 'pollution' that made life possible, according to new results from ESA. The gas that escapes contains elements heavier than hydrogen or helium and is positively ionized, including carbon, the essential element for life on Earth.
Black holes are not quite the all-consuming monsters depicted in popular culture.

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Researchers of the heart and headaches at Thomas Jefferson University Hospital are combining efforts to determine if a common heart defect may be the cause of some forms of migraine headaches.
Investigators from the Jefferson Heart Institute and the Jefferson Headache Center are enrolling participants in a blinded study to determine if closing a Patent Foramen Ovale (PFO), a small hole or flap that can allow blood to flow between the right and left sides of the heart, can stop migraines. In newborns, the PFO closes at or shortly after birth, but in 20 percent of adults the gap remains open to some degree.

The largest study to date of genetic variation among chimpanzees has found that the traditional, geography-based sorting of chimps into three populations—western, central and eastern—is underpinned by significant genetic differences, two to three times greater than the variation between the most different human populations.