Why Both Stimulating And Blocking GLP-1R Helps People Lose Weight
Understanding which brain circuits respond to weight loss medications and how they behave could lead to better weight loss with fewer side effects.
Understanding which brain circuits respond to weight loss medications and how they behave could lead to better weight loss with fewer side effects.
Women who have unprotected sexual intercourse or experience contraceptive failure can seek emergency contraception to reduce their chance of unintended pregnancy. Emergency contraception is a safe medication, and to be effective, must be taken within five days of unprotected intercourse. Several barriers can discourage use of emergency contraception, including an inability to obtain the medication fast enough. One proposed solution is to let women have a set of the tablets that they can keep for immediate use should it be needed.
Trials lasting 4 to 8 weeks indicate that including wholegrain oats in your diet may lower total and low-density lipoprotein cholesterol.
Coronary heart disease (CHD) is a major cause of death and ill health. One of the risk factors for CHD is elevated blood levels of total cholesterol and of low density lipoprotein cholesterol. Existing observational studies indicate that wholegrain cereals may reduce the risk of CHD, possibly by reducing cholesterol levels.
Temporal sequence represents the main principle underlying episodic memory. The storage of temporal sequence information is thought to involve hippocampus-dependent memory systems, preserving temporal structure possibly via chaining of sequence elements in heteroassociative networks.
Converging evidence indicates that sleep enhances the consolidation of recently acquired representations in the hippocampus-dependent declarative memory system. Yet, it is unknown if this consolidation process comprises strengthening of the temporal sequence structure of the representation as well, or is restricted to sequence elements independent of their temporal order.
Put a human and a chimpanzee side by side, and it seems obvious which lineage has changed the most since the two diverged from a common ancestor millions of years ago. Such apparent physical differences, along with human speech, language and brainpower, have led many people to believe that natural selection has acted in a positive manner on more genes in humans than in chimps.
But new research at the University of Michigan challenges that human-centered view.
Researchers from the Woods Hole Oceanographic Institution (WHOI) are venturing this month to the North Pole to deploy instruments that will make year-round observations of the water beneath the Arctic ice cap. Scientists will investigate how the waters in the upper layers of the Arctic Ocean—which insulate surface ice from warmer, deeper waters—are changing from season to season and year to year as global climate fluctuates.
The Arctic expedition is part of a multi-year, multi-institutional program to establish a real-time, autonomous Arctic Observing Network.
Climate change could trigger "boom and bust" population cycles that make animal species more vulnerable to extinction, according to Christopher C. Wilmers, an assistant professor of environmental studies at the University of California, Santa Cruz.
For the past three years a satellite has circled the Earth, collecting data to determine whether two predictions of Albert Einstein's general theory of relativity are correct.
Are you ready for "X-ray glasses" that see through fog - and even clothing? With their new world record in high-frequency submillimeter waves, researchers at the UCLA Henry Samueli School of Engineering and Applied Science are bringing that kind of imaging technology closer to reality.
The record-setting 324-gigahertz frequency was accomplished using a voltage-controlled oscillator in a 90-nanometer complementary metal-oxide semiconductor (CMOS) integrated circuit, a technology used in chips such as microprocessors.
An earthquake engineer at Washington University in St. Louis has successfully performed the first test of wireless sensors in the simulated structural control of a model laboratory building.
Shirley J. Dyke, Ph.D., the Edward C. Dicke Professor of Civil Engineering and director of the Washington University Structural Control and Earthquake Engineering Laboratory, combined the wireless sensors with special controls called magnetorheological dampers to limit damage from a simulated earthquake load.
Her demonstration is the first step toward implementing wireless sensors for structural control in real buildings and structures, enabling less manpower requirements and far less remodeling of existing structures.
Four-year-old girls are six times more likely to have a Body Mass Index (BMI) of more than 30 than they were 20 years ago and ten-year-olds are five times more likely, according to research published in the April issue of Acta Paediactrica.
Swedish researchers who studied BMI figures for more than a thousand children over two decades discovered that obesity levels had risen significantly among younger children, but that levels were much more constant among teenagers included in the research. They also found that young girls were much more likely to be overweight or obese than boys.
The high rate of diabetes among indigenous people is not due to their genetic heritage, according to a recently published study.
The study was authored by Dr Yin Paradies, an epidemiologist from Darwin's Menzies School of Health Research along with two researchers from the United States. It shows that the high rates of diabetes among indigenous people across the globe are rooted in social disadvantage rather than a genetic pre-disposition specific to indigenous populations.
A vaccine for treating a recurrent cancer of the central nervous system that occurs primarily in the brain has shown promise in preliminary data from a clinical trial at the University of California, San Francisco.
Known as a glioma, this cancerous tumor is always fatal. Findings from a group of 12 study patients showed that vitespen vaccination (trademarked as Oncophage) was effective in stimulating the patient’s immune system to attack the tumor cells, a function that is known medically as tumor-specific immune response. All the patients had recurrent, high-grade glioma, and all showed the immune response. The vaccine is made from the patient’s own tumor.