Why Both Stimulating And Blocking GLP-1R Helps People Lose Weight
Understanding which brain circuits respond to weight loss medications and how they behave could lead to better weight loss with fewer side effects.
Understanding which brain circuits respond to weight loss medications and how they behave could lead to better weight loss with fewer side effects.
In 2000, Georgia Tech researchers showed that fluid dynamics theory could be modified to work on the nanoscale, albeit in a vacuum. Now, seven years later they've shown that it can be modified to work in the real world, too – that is, outside of a vacuum. The results appear in the February 9 issue of Physical Review Letters (PRL).
Understanding the motion of fluids is the basis for a tremendous amount of engineering and technology in contemporary life. Planes fly and ships sail because scientists understand the rules of how fluids like water and air behave under varying conditions. The mathematical principle that describe these rules wave put forth more than 100 years ago and are known as the Navier-Stokes equations.
In a thought-provoking paper from the March issue of The Quarterly Review of Biology , Elliott Sober (University of Wisconsin) clearly discusses the problems with two standard criticisms of intelligent design: that it is unfalsifiable and that the many imperfect adaptations found in nature refute the hypothesis of intelligent design.
Biologists from Charles Darwin to Stephen Jay Gould have advanced this second type of argument. Stephen Jay Gould's well-known example of a trait of this type is the panda's thumb. If a truly intelligent designer were responsible for the panda, Gould argues, it would have provided a more useful tool than the stubby proto-thumb that pandas use to laboriously strip bamboo in order to eat it.
ID proponents have a ready reply to this objection.
Northern Nevada energy consumers can be excused if they have a sense of "sticker shock" when their power bills come due following the holiday season. Or, that they have a feeling of powerlessness as the price of gasoline climbs to $3 per gallon.
They wonder: will the days of the $1 tank of gas ever return?
Thanks to research done by a University of Nevada, Reno professor in the area of hydrogen energy generation, soaring power bills could become a thing of the past. And, finding a power source for your car that costs as little as $1 per gallon could also soon become a welcome reality.
Manoranjan Misra, professor of materials science and engineering, recently received a $3 million research grant from the U.S.
According to a new study published in the latest issue of The Journal of Sexual Medicine and conducted in the Department of Psychology of McGill University, thermography shows great promise as a diagnostic method of measuring sexual arousal. It is less intrusive than currently utilized methods, and is the only available test that requires no physical contact with participants. Thermography is currently the only method that can be used to diagnose sexual health problems in both women and men. In fact, women and men demonstrated similar patterns of temperature change during sexual arousal with no significant differences between genders in the time needed to reach peak temperature.
Researchers at the University at Buffalo and the University of Utah are beginning a clinical trial to test whether aspirin can improve a woman's chances of becoming pregnant and of maintaining a pregnancy to term.
UB's portion of the study is funded by a $2.8 million grant from the National Institute of Child Health and Development.
The trial is aimed at women who have miscarried a pregnancy in the past year.
"In women who have had their first miscarriage, the reasons for losing that pregnancy are in many instances unknown," said Jean Wactawski-Wende, Ph.D., UB associate professor of social and preventive medicine and principal investigator of the UB clinical center.
NASA's Spitzer Space Telescope has captured for the first time enough light from planets outside our solar system, known as exoplanets, to identify signatures of molecules in their atmospheres. The landmark achievement is a significant step toward being able to detect possible life on rocky exoplanets and comes years before astronomers had anticipated.
"This is an amazing surprise," said Spitzer project scientist Dr. Michael Werner of NASA's Jet Propulsion Laboratory, Pasadena, Calif.
Do hard money contributions by interest groups to members of Congress contribute to better quality policy deliberations and outcomes in congressional committees? A new study conducted by political scientist Kevin M.
Scientists from Université Laval’s Faculty of Medicine have succeeded in producing neurons in vitro using stem cells extracted from adult human skin. This is the first time such an advanced state of nerve cell differentiation has been achieved from human skin, according to lead researcher Professor François Berthod. This breakthrough could eventually lead to revolutionary advances in the treatment of neurodegenerative illnesses such as Parkinson’s disease. Berthod and his team described the method used to produce these neurons in a recent issue of the Journal of Cellular Physiology.
The researchers used skin obtained from plastic surgery procedures.
At any given time, most of the roughly 30,000 genes that constitute the human genome are inactive, or repressed, closed to the cellular machinery that transcribes genes into the proteins of the body. In an average cell, only about one in ten genes is active, or expressed, at any given moment, with its DNA open to the cell' transcriptional machinery.
A dynamic cast of gatekeeper enzymes controls this access to the DNA, adding and removing particular molecules to open or close the genome to transcription as needed. Fully explicating the complex interplay among these enzymes and the molecules they manage has been a primary goal for scientists seeking to understand the mechanisms governing gene control.
Drilling is complete on an Alaskan North Slope well, cofunded by the Department of Energy, that could prove to be an important milestone in assessing America's largest potential fossil energy resource: gas hydrate.
Gas hydrate is an ice-like solid that results from the trapping of methane molecules - the main component of natural gas - within a lattice-like cage of water molecules. Dubbed the "ice that burns," this substance releases gaseous methane when it melts.
The size of the global gas hydrate resource is staggering, holding more ultimate energy potential than all other fossil fuels combined, according to the U.S. Geological Survey (USGS).
Researchers at the University of East Anglia are about to embark on an innovative new project to develop computer lip-reading systems that could be used for fighting crime.
The three-year project, which starts next month, will collect data for lip-reading and use it to create machines that automatically convert videos of lip-motions into text. It builds on work already carried out at UEA to develop state-of-the-art speech reading systems.
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African and African American women are more likely to die of breast cancer than their white counterparts because they tend to get the disease before the menopause, suggests new research from the University of East Anglia and the Children’s Hospital Boston in collaboration with researchers in the US and Italy.
A racial disparity in mortality rates from breast cancer in the US first appeared in the 1970s coinciding with the introduction of mammography.