More men than women develop Parkinson’s disease and new work presented at the Federation of European Neuroscience Societies says that it is do to sex differences in how brain cells change. Parkinson’s disease affects about 9 million people and becomes increasingly prevalent with age.
Coronary or peripheral bypasses are the most frequently performed vascular operations. Although one million patients per year and around the world, undergo this intervention, its failure rate reaches 50%, because of poor vessel healing, leading to vessel graft occlusion. To improve the outcome of bypasses, researchers from the University of Geneva (UNIGE) work together with medical doctors from the Lausanne University Hospital (CHUV). They developed a gel containing microparticles -'GeM', enabling the controlled release of a drug inhibiting cellular over-proliferation. Administered locally, directly on the bypass graft during surgery, this preventive treatment will reduce the risk of obstruction reoccurrence. This research can be read in The Journal of Controlled Release.
In a randomized Phase III study of the drug inotuzumab ozogamicin, a statistically significant percentage of patients with acute lymphoblastic leukemia (ALL) whose disease had relapsed following standard therapies, qualified for stem cell transplants.
Inotuzumab ozogamicin, also known as CMC-544, links an antibody that targets CD22, a protein found on the surface of more than 90 percent of ALL cells. Once the drug connects to CD22, the ALL cell draws it inside and dies.
It's no surprise that the rise of peanut allergies correlates to the rise in helicopter parenting. Where kids once built up immunity by getting dirty and eating the foods their parents, a subset of modern parents schedule play dates, buy antibacterial soap and believe that breast milk has "otherworldly power."
The frequency of nuisance tidal flooding in many U.S. cities was predicted for the 2015 meteorological year, from May 2015 to April 2016, according to a new NOAA report.
Simon Fraser University research aimed at helping people get to sleep will be highlighted at an international sleep conference next week. Luc Beaudoin, an adjunct professor in cognitive science and education, created the mySleepButton® app two years ago (a new version with the world's first configurable "body scan" will be released shortly).
It uses what he calls a "cognitive shuffle," or Serial Diverse Imagining (SDI), a method that essentially "scrambles" one's thoughts and keeps the mind off issues that may prevent sleep. "A racing mind, worries and uncontrollable thoughts are common bedtime complaints among poor sleepers," Beaudoin notes.
Hellisheidi power plant in Iceland is the world's largest geothermal facility and now it has one other distinction. Engineers there have shown that carbon dioxide emissions can be pumped into the earth and changed chemically to stone within months, far faster than believed.
Researchers have developed a compound that can transform near-infrared light into broadband white-light, offering a cheap, efficient means to produce visible light. The emitted light is also exceedingly directional, a desirable quality for devices like microscopes that require high spatial resolution, or for applications with high throughput, such as projection systems. Nils Wilhelm Rosemann and colleagues designed their compound of tin and sulfur, and with a diamondoid-like structure, then coating this scaffolding with organic ligands. When a laser directs near-infrared light into the compound, the structure of the compound alters the wavelength of the light through a non-linear interaction process, producing light at wavelengths that are visible to the human eye.
RIVERSIDE, Calif. - Toxoplasma gondii, a protozoan parasite about five microns long, infects a third of the world's population. Ingested via undercooked meat or unwashed vegetables, the parasite infects 15-30 percent of the US population. In France and Brazil, up to 80 percent of the population has the infection.
Particularly dangerous during pregnancy - infection in pregnant women can cause serious congenital defects and even death of the fetus - this chronic infection has two components: the unicellular parasite, and inflammation of tissues it causes.
An isolated population of honeybees, the Cape bees, living in South Africa has evolved a strategy to reproduce without males. A research team from Uppsala University has sequenced the entire genomes of a sample of Cape bees and compared them with other populations of honeybees to find out the genetic mechanisms behind their asexual reproduction.
Most animals reproduce sexually, which means that both males and females are required for the species to survive. Normally, the honeybee is no exception to this rule: the female queen bee produces new offspring by laying eggs that have been fertilised by sperm from male drones. However, one isolated population of honeybees living in the southern Cape of Africa has evolved a strategy to do without males.
Magicians could join composers and artists in finding new ideas for their performances by using computers to create new magic effects, according to computer scientists at Queen Mary University of London (QMUL).
Writing in the open access journal Frontiers in Psychology, the scientists, one of whom is also practicing magician, have looked at modelling particular human perceptual quirks and processes, and building computer systems able to search and find designs for new tricks based on these potential responses from the audience.
The rise of big data and advances in information technology has serious implications for our ability to deliver sufficient bandwidth to meet the growing demand.
Researchers at the University of the Witwatersrand in Johannesburg, South Africa, and the Council for Scientific and Industrial Research (CSIR) are looking at alternative sources that will be able to take over where traditional optical communications systems are likely to fail in future.
In their latest research, published online today (10 June 2016) in the scientific journal, Scientific Reports, the team from South Africa and Tunisia demonstrate over 100 patterns of light used in an optical communication link, potentially increasing the bandwidth of communication systems by 100 times.
CHICAGO --- About 80 percent of patients with moderate to severe psoriasis saw their disease completely or almost completely cleared with a new drug called ixekizumab, according to three large, long-term clinical trials led by Northwestern Medicine.
The results of these phase III trials were compiled in a paper published in the New England Journal of Medicine.
"This group of studies not only shows very high and consistent levels of safety and efficacy, but also that the great majority of the responses persist at least 60 weeks," said Dr. Kenneth Gordon, a professor of dermatology at Northwestern University Feinberg School of Medicine and first author of the paper.
