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Inbred Neanderthals Left Humans A Genetic Burden

Inbred Neanderthals Left Humans A Genetic Burden

The Neanderthal genome included harmful mutations that made the hominids around 40% less reproductively fit than modern humans, according to estimates published in the latest issue of the journal GENETICS. Non-African humans inherited some of this genetic burden when they interbred with Neanderthals, though much of it has been lost over time. The results suggest that these harmful gene variants continue to reduce the fitness of some populations today. The study also has implications for management of endangered species.

IL-33 Ameliorates Alzheimer's-like Pathology And Cognitive Decline

IL-33 Ameliorates Alzheimer's-like Pathology And Cognitive Decline

Alzheimer's disease (AD) is a devastating condition with no known effective treatment. The disease is characterized by memory loss as well as impaired locomotor ability, reasoning, and judgment. Emerging evidence suggests that the innate immune response plays a major role in the pathogenesis of AD.

Blood Test To Personalize Depression Treatment For The First Time

Blood Test To Personalize Depression Treatment For The First Time

Scientists at King's College London have developed a blood test that accurately and reliably predicts whether depressed patients will respond to common antidepressants, which could herald a new era of personalised treatment for people with depression.
Guided by this test, patients with blood inflammation above a certain threshold could be directed towards earlier access to more assertive antidepressant strategies, such as a combination of antidepressants, before their condition worsens.

Cleaning Up Decades Of Phosphorus Pollution In Lakes

Cleaning Up Decades Of Phosphorus Pollution In Lakes

Oxford, June 6, 2016 - Phosphorus is the biggest cause of water quality degradation worldwide, causing 'dead zones', toxic algal blooms, a loss of biodiversity and increased health risks for the plants, animals and humans that come in contact with polluted waters. This threatens the loss of economic and social benefits from freshwaters upon which society relies. In a series of studies published in a special issue of Water Research, leading scientists assess how geo-engineering in lakes can control phosphorus pollution.

Anxiety - Women, Young People Impacted Most

Anxiety - Women, Young People Impacted Most

Anxiety may be a first world problem - and a young female one at that.
A review of reviews (so calibrate your expectations) in Brain and Behavior finds that women are almost twice as likely to experience anxiety as men, and people from Western Europe and North America are more likely to suffer from anxiety than people from other cultures.
Anxiety disorders are a non-specific blanket term for excessive worry, fear and a tendency to avoid potentially stressful situations including social gatherings. Pretend money estimates claim these disorders cost $42.3 million in the U.S. In the European Union, over 60 million people are affected by anxiety disorders in a given year, likely because of all that worry about cell phones, ugly fruit and GMOs.

Food And Beverage Products Marketed By Musicians Are Unhealthy

Food And Beverage Products Marketed By Musicians Are Unhealthy

You don't see a lot of celebrities advertising kale - which is okay, kale is not all that healthy, but at least it has a health halo. Not so for soda and other sugary drinks, fast food and sweets, and those are among the most common food and beverage products endorsed by famous music personalities.
They are directly to blame for obesity, claims lead author Marie Bragg, PhD, assistant professor in the Department of Population Health at NYU Langone, in Pediatrics.
Unsurprisingly, Big Lettuce did not hire celebrities to do endorsements, nor did music stars endorse fruits, vegetables, or whole grains. Only one endorsed a natural food deemed healthy -pistachios - over a 14-year period covering dozens of advertisements. Yes, dozens.  

Stress Hormone Link With Psychosis

Stress Hormone Link With Psychosis

JCU Associate Professor Zoltan Sarnyai said it was the first meta-analysis study to compare the level of cortisol in a waking patient's body with the stage of schizophrenia they are suffering.
Dr Sarnyai said it means doctors may be able to eventually identify those who will develop full-blown psychosis from amongst those who present with early stages of the disease.
"Only some 20 to 30 per cent of individuals who are at high-risk of developing psychosis due to their clinical presentation or family history actually do so. Identifying those people early is where the cortisol measurement comes in.

The Universe Is Expanding Even Faster Than Believed

The Universe Is Expanding Even Faster Than Believed

Astronomers have used Hubble to measure the distances to stars in nineteen galaxies more accurately than previously possible. They found that the Universe is currently expanding faster than the rate derived from measurements of the Universe shortly after the Big Bang. If confirmed, this apparent inconsistency may be an important clue to understanding three of the Universe's most elusive components: dark matter, dark energy and neutrinos.

Dentin Nanostructures -- A Super-natural Phenomenon

Dentin Nanostructures -- A Super-natural Phenomenon

Dentin is one of the most durable biological materials in the human body. Researchers from Charité - Universitätsmedizin Berlin were able to show that the reason for this can be traced to its nanostructures and specifically to the interactions between the organic and inorganic components. Measurements performed at BESSYII, the Helmholtz-Zentrum Berlin's synchrotron radiation source, showed that it is the mechanical coupling between the collagen protein fibers and mineral nanoparticles which renders dentin capable of withstanding extreme forces. Results from this research have been recently published in the journal Chemistry of Materials*.

New Pre-surgery Technique May Make Colostomy Bags Redundant For Emergency Bowel Cancer Patients

New Pre-surgery Technique May Make Colostomy Bags Redundant For Emergency Bowel Cancer Patients

AN expandable tube that unblocks the bowel before surgery could lead to fewer cancer patients -- diagnosed as emergencies -- needing a colostomy bag.
The Cancer Research UK-funded CReST trial presented at the 2016 American Society of Clinical Oncology (ASCO) Annual Meeting in Chicago today (Sunday)* found that less than half (45 per cent) of those who had their bowel unblocked by the tube, which uses body heat to expand, needed a colostomy bag.
But more than two-thirds (69 per cent) of those who had emergency surgery to remove the tumour and the blockage were fitted with bags.
Around 41,100 people are diagnosed with bowel cancer each year in the UK with up to 20 per cent diagnosed as emergencies -- with some of these patients having their bowel blocked by the tumour.