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Fecal Transplantation: Fresh Vs. Frozen

Fecal Transplantation: Fresh Vs. Frozen

Among adults with Clostridium difficile infection that is recurrent or not responsive to treatment, the use of frozen compared with fresh fecal microbiota transplantation (FMT) did not result in a significantly lower rate of resolution of diarrhea, indicating that frozen FMT may be a reasonable treatment option for these patients. 

Singin' In The Brain

Singin' In The Brain

A songbirds' vocal muscles work like those of human speakers and singers, finds a new study. The research on Bengalese finches showed that each of their vocal muscles can change its function to help produce different parameters of sounds, in a manner similar to that of a trained opera singer.
Pitch, for example, is important to songbird vocalization, but there is no single muscle devoted to controlling it. They don't just contract one muscle to change pitch, they have to activate a lot of different muscles in concert, and these changes are different for different vocalizations. Depending on what syllable the bird is singing, a particular muscle might increase pitch or decrease pitch.

Childhood Leukemias: Different Forces Than Adults

Childhood Leukemias: Different Forces Than Adults

For half a century, cancer researchers have struggled with a confusing paradox: If cancer is caused by the occurrence and accumulation of cancer-causing (oncogenic) mutations over time, young children should get less cancer since they have fewer mutations.
So why do young children have a higher incidence of leukemia than teenagers and young adults? 

Statins May Lower Risk Of Heart Disease In People With Sleep Apnea

Statins May Lower Risk Of Heart Disease In People With Sleep Apnea

NEW YORK, NY (Jan. 6, 2016) -- A new study conducted at Columbia University Medical Center (CUMC) has revealed some of the underlying mechanisms that may increase the risk of heart disease in people with sleep apnea. The study also found that statins -- the cholesterol-lowering medications commonly prescribed to combat heart disease -- may help reverse this process.
The study was published in the Jan. 6, 2016 online edition of Science Translational Medicine.

New Type Of Antidepressant Found To Act Quickly In Mice

New Type Of Antidepressant Found To Act Quickly In Mice

The compound CGP3466B, already proven nontoxic for people, may effectively and rapidly treat depression, according to results of a study in mice.
The Johns Hopkins Medicine neuroscientists who conducted the research say that the compound -- previously shown to block cocaine craving in the brains of rodents -- delivers antidepressant effects to mice within hours instead of weeks or months, like currently available antidepressants. The results of the study will be summarized Jan. 12 online in the journal Molecular Psychiatry.

Inflammation Markers Could Guide Depression Treatments

Inflammation Markers Could Guide Depression Treatments

Psychiatrists investigating depression have been energized in recent years by reports of rapid, successful treatment with drugs that interfere with the brain chemical glutamate, such as the anesthetic ketamine.
New research from Emory University School of Medicine is providing hints as to which forms of depression may respond best to drugs that target glutamate.
The findings are scheduled for publication online on January 12 in Molecular Psychiatry.
Depressed patients with signs of systemic inflammation have elevated levels of glutamate in regions of the brain that are important for motivation, the researchers have found.

Roman Toilets Didn't Prevent Parasites

Roman Toilets Didn't Prevent Parasites

The Romans created a clear line between Iron Age and modern sanitation and hygiene. They built public multi-seat latrines with washing facilities and sewerage systems, they piped drinking water from aqueducts and heated public baths for washing.
To augment that, they developed laws designed to keep their towns free of excrement and rubbish.
But it may not have helped when it came to putting a stop to intestinal parasites such as whipworm, roundworm and Entamoeba histolytica dysentery, according to a journal in the journal Parasitology.

Coffee Berry Borer Consumes Enough Caffeine To Kill A Human Without Harm

Coffee Berry Borer Consumes Enough Caffeine To Kill A Human Without Harm

The coffee berry borer (Hypothenemus hampei) is a plague that affects coffee crops. It has a detoxification system based on microbial communities so it can perform its life cycle in the plant while exposed to high levels of caffeine. In human terms, the caffeine is equivalent to 500 espressos , which would kill a person."The aim was to study which are they and how they are associated with the digestive tract of the insect. For the study we took samples of insects from different locations like Hawaii, Indonesia, Puerto Rico, Mexico, Kenya, India and Guatemala," Javier A. Ceja Navarro of Berkeley National Laboratory told Investigación y Desarrollo.

Malaria Treatment Fails Due To Drug-Resistant Parasites

Malaria Treatment Fails Due To Drug-Resistant Parasites

It may be time to embrace DDT again. New findings from the National Institute of Allergy and Infectious Diseases (NIAID) confirm dihydroartemisinin-piperaquine, the first-line treatment for Plasmodium falciparum malaria infection in Cambodia, has failed in certain provinces due to parasite resistance to artemisinin and piperaquine.

Brain Connectivity Changes Protect Against Developing Bipolar Disorder

Brain Connectivity Changes Protect Against Developing Bipolar Disorder

Naturally occurring changes in brain wiring can help patients at high genetic risk of developing bipolar disorder avert the onset of the illness, according to a new study in Translational Psychiatry.  
Bipolar disorder, also known as manic-depressive illness, is a brain disorder that causes fluctuations in patients' mood, energy, activity levels and the ability to carry out day-to-day tasks. Bipolar disorder is highly heritable, meaning that people with a parent or sibling with bipolar disorder have a much greater risk of developing the illness, compared with individuals with no family history.

Small Males Have More Sex Appeal

Small Males Have More Sex Appeal

Females don't always think bigger is better when it comes to males. Instead, it is just the opposite, in some instances. Females may be more attracted to small partners because they are less likely to get into fights.
In many species large males have more mating success than small males, either because females find them more attractive or because they can use their brawn to intimidate small rivals. They are also more likely to have more sexual partners and be less committed fathers.