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What Next For Messenger RNA (mRNA)? Maybe Inhalable Vaccines

No one likes getting a needle but most want a vaccine. A new paper shows progress for messenger...

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Attorney Robert F. Kennedy Jr. and his US followers over the last 25 years have staunchly opposed...

ChatGPT Is Cheaper In Medicine And Does Better Diagnoses Even Than Doctors Using ChatGPT

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Cigarettes are the top lifestyle risk factor for getting cancer, though alcohol and obesity have...

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For 3 billion years, one of the major carriers of information needed for life, RNA, has had a glitch that creates errors when making copies of genetic information. Researchers at The University of Texas at Austin have developed a fix that allows RNA to accurately proofread for the first time. The new discovery, published June 23 in the journal Science, will increase precision in genetic research and could dramatically improve medicine based on a person's genetic makeup.

Certain viruses called retroviruses can cause RNA to make copies of DNA, a process called reverse transcription. This process is notoriously prone to errors because an evolutionary ancestor of all viruses never had the ability to accurately copy genetic material.

BLOOMINGTON, Ind. -- Indiana University researchers have that found a suite of genes in both fruit flies and humans -- including one dubbed "smoke alarm" -- plays a role in nerve sensitivity. The study could help lead to new drug targets in pain management.

The research, published today in the journal Cell Reports, was led by W. Daniel Tracey Jr., a professor in the IU Bloomington College of Arts and Sciences' Linda and Jack Gill Center for Biomolecular Science and the Department of Biology.

A team of researchers has developed the first scalable method to identify different subtypes of neurons in the human brain. The research lays the groundwork for "mapping" the gene activity in the human brain and could help provide a better understanding of brain functions and disorders, including Alzheimer's, Parkinson's, schizophrenia and depression.

By now we are used to the idea of seasonal weather forecasts - whether to expect an El Niño ski season, or an unusually warm summer. These same types of climate models are now being adapted to make seasonal forecasts for the region's coastal waters.

Researchers from the University of Washington and the National Oceanic and Atmospheric Administration have created a seasonal outlook for the Pacific Northwest waters, which would help tell if it's going to be a great year for sardines or a poor crab season. A paper evaluating the forecast's performance was published in June in the interdisciplinary, open-access journal Nature: Scientific Reports.

PITTSBURGH, June 23, 2016 - Potent doses of broccoli sprout extract activate a "detoxification" gene and may help prevent cancer recurrence in survivors of head and neck cancer, according to a trial by the University of Pittsburgh Cancer Institute, partner with UPMC CancerCenter, confirming preliminary results presented last year at the American Association for Cancer Research Annual Meeting.

It is the first study demonstrating that the extract protects against oral cancer, with the results of human, animal and laboratory tests reported today in the journal Cancer Prevention Research. This research is funded through Pitt's Specialized Program of Research Excellence grant in head and neck cancer from the National Cancer Institute.

Future global warming will not only depend on the amount of emissions from man-made greenhouse gasses, but will also depend on the sensitivity of the climate system and response to feedback mechanisms. By reconstructing past global warming and the carbon cycle on Earth 56 million years ago, researchers from the Niels Bohr Institute among others have used computer modelling to estimate the potential perspective for future global warming, which could be even warmer than previously thought. The results are published in the scientific journal, Geophysical Research Letters.