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What Next For Messenger RNA (mRNA)? Maybe Inhalable Vaccines

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"Hope is being given to patients with malignant and ultimately fatal spinal tumors where hope was never before available," said Dr. Isabelle Germano, Professor of Neurosurgery and Co-Director of The Radiosurgery Program at The Mount Sinai Medical Center. "All it takes is one thirty-minute out-patient treatment of pinpointed radiation and the tumor shrinks along with the pain from the cancer. Now cancer spreading to the spine doesn't mean a lifetime of pain or a wheelchair for a patient anymore."

Implanting dopamine generators (dopaminergics) in brain cells has produced improvement in the symptoms in Parkinson's, according to the results of tests carried out with monkeys by the Navarra University Hospital, led by Dr María Rosario Luquin Piudo, neurologist at the Hospital and at the other Navarra University-based medical centre, CIMA (the Research Centre for Applied Medicine).

The results have been published in the latest issue of the British scientific journal specialising in Neurology, Brain, and have corroborated the conclusions of a previous study, published in 1999 by the same research team in the specialist journal, Neuron.

A challenging goal in biology is to understand how the principal cellular functions are integrated so that cells achieve viability and optimal fitness under a wide range of nutritional conditions. Scientists from the French research centers INRA and CNRS showed by genetic approaches that, in the model bacterium Bacillus subtilis, central carbon metabolism (which generates energy from nutrients) and replication (which synthesizes DNA), two key functions in the fields of nutrition and heredity, are tightly linked.

The discovered link involves the activity of a small region of the central carbon metabolism (the terminal reactions of a process called glycolysis that burns sugars) and several enzymes of the replication machinery that synthesizes DNA.

Despite hundreds of families being told their children have peanut allergies every year, many of the children may be able to eat peanuts safely, a study by researchers at the University of New South Wales (UNSW) and Sydney Children's Hospital has found.

Peanut allergies occur in one in 200 infants, according to the Australasian Society of Clinical Immunology and Allergy.

Clinical research conducted in the Department of Communication Disorders at the University of Haifa revealed that some children who are born deaf "recover" from their deafness and do not require surgical intervention.

To date, most babies who are born deaf are referred for a cochlear implant. "Many parents will say to me: 'My child hears; if I call him, he responds'. Nobody listens to them because diagnostic medical equipment did not register any hearing. It seems that these parents are smarter than our equipment," said Prof. Joseph Attias, a neurophysiologist and audiologist in the Department of Communication Disorders at the University of Haifa, who made the discovery.

Scientists from the University of Nebraska-Lincoln and the National Agricultural Research Organization in Uganda teamed up with local, eastern Ugandan farmers to evaluate the effectiveness of low-cost alternatives for soil treatment. By implementing alternative soil fertility management and a reduction in crop tillage, scientists hope to help small-scale farmers to increase crop outputs.