"What might have been" or fictive learning affects the brain and plays an important role in the choices individuals make – and may play a role in addiction, said Baylor College of Medicine researchers and others in a report that appears online today in the Proceedings of the National Academy of Sciences.

These "fictive learning" experiences, governed by what might have happened under different circumstances, "often dominate the evaluation of the choices we make now and will make in the future, " said Dr. P. Read Montague, Jr., professor of neuroscience at BCM and director of the BCM Human Neuroimaging Laboratory and the newly formed Computational Psychiatry Unit.

A Mediterranean diet halves the chances of developing progressive inflammatory lung disease (COPD), reveals a large study, published ahead of print in Thorax.

COPD (chronic obstructive pulmonary disease) is an umbrella term for chronic progressive lung disease, such as emphysema and bronchitis. It is expected to become the third leading cause of death worldwide by 2020, with cigarette smoking the primary factor in its development.

A NASA-funded expedition, including researchers from Carnegie Mellon University’s Robotics Institute, will begin searching for the submerged bottom of Mexico’s El Zacatón sinkhole with a robotic submarine the week of May 14.

Zacatón, in the Mexican state of Tamaulipas, is a geothermal sinkhole, or cenote, that is more than 282 meters deep. Nobody has ever reached bottom and at least one diver has died attempting to do so. Scientists want to learn more about its physical dimensions, the geothermal vents that feed it and whatever life might exist at its various depths.

Cultural differences between countries run right to the heart of government, thereby influencing technological innovation. This is reported in a comparative study by David Calef and Robert Goble published recently in the journal Policy Sciences(1). The authors outline efforts taken throughout the 1990s by both the US and French governments to adopt legislation fostering technological innovation to improve urban air quality by promoting clean vehicles, specifically electric vehicles (EVs). The study highlights the differences in approach and policy-making style by both governments and how this might have affected the final outcome.

Threatened coral reefs could be given a helping hand by establishing marine reserves, according to a research team led by the University of Exeter. Marine reserves have already proved to be a successful way of protecting marine life against commercial fishing. Marine reserves could also help in the recovery of corals, which are already suffering the effects of climate change and over-fishing.

With the advent of more powerful and economical DNA sequencing technologies, gene discovery and characterization is transitioning from single-organism studies to revealing the potential biotechnology applications embedded in communities of microbial genomes, or metagenomes. The field of metagenomics is still in its infancy -- the equivalent of the early days of the California Gold Rush, with labs vying to stake their claim.

Amidst the prospecting, the call has been issued for methods to separate fool's gold from the real nuggets. Such a gold standard has now been provided through work led by the U.S. Department of Energy Joint Genome Institute (DOE JGI) with colleagues from Oak Ridge National Laboratory and IBM's T.J. Watson Research Center.