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Flight - And Dive - Of The RoboBee

Flight - And Dive - Of The RoboBee

In 1939, a Russian engineer proposed a "flying submarine" -- a vehicle that can seamlessly transition from air to water and back again. While it may sound like something out of a James Bond film, engineers have been trying to design functional aerial-aquatic vehicles for decades with little success. Now, engineers may be one step closer to the elusive flying submarine.
The biggest challenge is conflicting design requirements: aerial vehicles require large airfoils like wings or sails to generate lift while underwater vehicles need to minimize surface area to reduce drag.

Building Immune System Memory

Building Immune System Memory

Vaccines help prevent disease by inducing immunological memory, the ability of immune cells to remember and respond more quickly when re-exposed to the same pathogen. While certain phases of the pathway are well understood, little is known about the role of helper T cells, a "master orchestrator" of the immune response that send signals to activate the immune system.
A study has identified molecular mechanisms that control an immune cell's ability to remember. They found that in helper T (CD4+) cells, the proteins Oct1 and OCA-B work together to put immune response genes on standby so that they are easily activated when the body is re-exposed to a pathogen.

Test Could Predict Whether Breast Cancer  Will Spread To The Brain

Test Could Predict Whether Breast Cancer Will Spread To The Brain

Women with particularly aggressive forms of breast cancer could be identified by a test that predicts whether the disease is likely to spread to the brain.
An analysis of almost 4,000 patients with breast cancer found that testing for high activity in a particular gene called alpha beta (αB)-crystallin could pick out women who were at greater risk of developing secondary brain tumors compared to women who tested negative.
A team including scientists at The Institute of Cancer Research, London, found that women whose breast cancer had begun to spread and who tested positive in the αB-crystallin test were three times more likely to have disease that spread to the brain than those who tested negative.

Bees: 'We're More Complicated Than You Think'

Bees: 'We're More Complicated Than You Think'

Chemical signaling among social insects, such as bees, ants and wasps, is more complex than previously thought, according to researchers whose results refute the idea that a single group of chemicals controls reproduction across numerous species.

Cleaning Up The Dirty Business Of Making New Clothes

Cleaning Up The Dirty Business Of Making New Clothes

Processing fabric for the latest fashions and other textile-based products today requires thousands of chemicals, some of which are toxic and cause 20 percent of the world's water pollution. To reduce its environmental footprint, the textile industry is making changes, designing safer chemicals and turning to nature to find replacements to potentially harmful compounds, according to an article in Chemical&Engineering News.

Family Risk Of Breast Cancer Doesn't Affect The Self-Esteem Of Pre-Teen Girls - Yet

Family Risk Of Breast Cancer Doesn't Affect The Self-Esteem Of Pre-Teen Girls - Yet

Girls from families with a history of breast cancer, or genetic mutations that increase the risk of a breast cancer diagnosis, seem to adjust just as well as other girls when it comes to general anxiety, depression and overall psychosocial adjustment, according to new research from the Perelman School of Medicine at the University of Pennsylvania and the Children's Hospital of Philadelphia. However, the study also found that girls from at-risk families tend to worry more about breast cancer, particularly when their mothers have the same worries. 

Botox May Prevent Irregular Heartbeat After Bypass Surgery

Botox May Prevent Irregular Heartbeat After Bypass Surgery

Botulinum toxin, commonly known as Botox, is produced by Clostridium botulinum bacteria and was once known for disease but is now known for making Hollywood actresses look plastic. However, it may also prevent irregular heart rhythms when injected into fat surrounding the heart after bypass surgery, according to research in Circulation: Arrhythmia and Electrophysiology.
When a small amount of Botox is injected into a muscle, it blocks nerve signals that tell muscles to contract. Atrial fibrillation (also called AFib or AF) is a quivering or irregular heartbeat (arrhythmia) that can lead to blood clots, stroke, heart failure and other heart-related complications.

A New Way To Starve Lung Cancer?

A New Way To Starve Lung Cancer?

Scientists have identified a new way to stop the growth of lung cancer cells, by blocking their ability to use alternative sources of nutrition. The discovery was made possible by identifying the metabolic programs used by cancer cells to fuel their growth. The findings point to possible new avenues for treating lung cancer, which is the second most common cancer and accounts for over one-quarter of all cancer-related deaths. The results of the study were published Oct. 15 in the journal Molecular Cell.

What cancer cells 'eat'

Dietary Fat Impacts Autoimmune Flare-ups In Mice

Dietary Fat Impacts Autoimmune Flare-ups In Mice

Dietary fat may impact the severity and duration of autoimmune flare-ups, suggests a study published on October 20 in the journal Immunity. Adjusting the length of fatty acids consumed by mice altered the function of T helper cells in the gut--either intensifying or alleviating symptoms in an animal model of the autoimmune disease (i.e., multiple sclerosis).
A team led by Ralf Linker, of Friedrich-Alexander-University Erlangen-Nuremberg and his colleague Aiden Haghikia from the Ruhr-University Bochum in Germany compared in mice the effects of short-chain fatty acids, which are solely metabolized by gut bacteria and are typically found in fiber-rich diets, with the effects of long-chain fatty acids, the most abundant component of western diets.

Formation Of Coastal Sea Ice In North Pacific Drives Ocean Circulation And Climate

Formation Of Coastal Sea Ice In North Pacific Drives Ocean Circulation And Climate

An unprecedented analysis of North Pacific ocean circulation over the past 1.2 million years has found that sea ice formation in coastal regions is a key driver of deep ocean circulation, influencing climate on regional and global scales. Coastal sea ice formation takes place on relatively small scales, however, and is not captured well in global climate models, according to scientists at the
University of California, Santa Cruz, who conducted the study.
A paper on the new findings will be published in a future issue of the journal Paleoceanography and is currently available online.

Male And Female Hearts Don't Age The Same Way

Male And Female Hearts Don't Age The Same Way


An analysis of MRI scans of the aging hearts of nearly 3,000 adults shows significant differences in the way male and female hearts change over time. In both sexes, the main heart chamber, the left ventricle -- which fills with and then forces out blood -- gets smaller with time. As a result, less blood enters the heart and less gets pumped out to the rest of the body. But in men, the study reveals, the heart muscle that encircles the chamber grows bigger and thicker with age, while in women, it get retains its size or gets somewhat smaller.

Bees Love Caffeinated Nectar

Bees Love Caffeinated Nectar

Many humans like to start the day with a jolt of caffeine and it turns out bees do also.
They may even select caffeinated nectar over an uncaffeinated but otherwise equal alternative. As a result, researchers say, plants may be lacing their nectar with caffeine as a way to pass off cheaper goods.
"We describe a novel way in which some plants, through the action of a secondary compound like caffeine that is present in nectar, may be tricking the honey bee by securing loyal and faithful foraging and recruitment behaviors, perhaps without providing the best quality forage," says Margaret Couvillon of the University of Sussex.