Scientists have reported that an experimental vaccine targeting one of the most common genetic drivers of pancreatic cancer, called mutant KRAS, is safe and generated a durable immune responses aimed at preventing the cancer.
A person's face is the first thing that others see, and much remains unknown about how it forms — or malforms — during early development. Recently, Chong Pyo Choe, a senior postdoctoral fellow working in the lab of USC stem cell researcher Gage Crump, has begun to unwind these mysteries.
In a September study published in the journal Development, Choe and Crump describe how a mutation in a gene called TBX1 causes the facial and other deformities associated with DiGeorge syndrome.
Carbon dioxide emissions, the greenhouse gas that has been most strongly implicated in global warming, will reach a record high of 40 billion tons.
Physicists at the University of Geneva have succeeded in teleporting the quantum state of a photon to a crystal over 25 kilometers of optical fiber.
The experiment shatters the previous record of 6 kilometers achieved 10 years ago by the same team. Passing from light into matter, using teleportation of a photon to a crystal, shows that, in quantum physics, it is not the composition of a particle which is important, but rather its state, since this can exist and persist outside such extreme differences as those which distinguish light from matter.
The latest experiments have enabled verifying that the quantum state of a photon can be maintained whilst transporting it into a crystal without the two coming directly into contact.
Breast cancer experts around the world have issued a plea to researchers, academics, drug companies, funders and advocates to carry out high quality research and clinical trials for advanced breast cancer, a disease which is almost always fatal and for which there are many unanswered questions.
In the latest international consensus guidelines for the management of advanced breast cancer, published simultaneously in the leading cancer journals The Breast and Annals of Oncology [1] today (Friday), the experts say that further research and clinical trials are "urgently needed" to find the best treatments for:
patients with breast cancer that has spread to the liver, or the space around the lungs (pleural cavity) or the skin;
The sense of fairness did not evolve for the sake of fairness per se but in order to reap the benefits of continued cooperation, so say Frans de Waal, PhD, and Sarah Brosnan, PhD, co-authors of a review article about inequity aversion (IA), which is defined as a negative reaction to unequal outcomes. The review is published in Science.
Their conclusion comes after the co-authors reviewed more than 35 IA-related studies to address their hypothesis that it is the evolution of forestalling partner dissatisfaction with obtained outcomes and its negative impact on future cooperation that allowed the development of a complete sense of fairness in humans.
An international collaboration led by research groups from Mainz and Darmstadt, Germany, has achieved the synthesis of a new class of chemical compounds for superheavy elements at the RIKEN Nishina Center for Accelerator-based Research (RNC) in Japan. For the first time, a chemical bond was established between a superheavy element – seaborgium (element 106) in the present study – and a carbon atom. Eighteen atoms of seaborgium were converted into seaborgium hexacarbonyl complexes, which include six carbon monoxide molecules bound to the seaborgium. Its gaseous properties and adsorption to a silicon dioxide surface were studied, and compared with similar compounds of neighbors of seaborgium in the same group of the periodic table.
Imagine you are a species which over thousands of years has adapted to the arctic cold, and then you get exposed to a substance that makes the cold dangerous for you.
This is happening to the small white worm Enchytraeus albidus, and the cold provoking substance, called nonylphenol, comes from the use of certain detergents, pesticides and cosmetics.
Nonylphenol is suspected of being a endocrine disruptor, but when entering the worm it has another dangerous effect: It inhibits the worm's ability to protect the cells in its body from cold damage.
Many patients with advanced, incurable cancer do not receive any palliative care, reveals new research to be presented later this month at the ESMO 2014 Congress in Madrid, Spain, 26-30 September. The findings are astonishing as they come at the same time as 15 new oncology centres in Europe, Canada, South America and Africa are being awarded the prestigious title of 'ESMO Designated Centre of Integrated Oncology and Palliative Care.'
There is nothing inherently superior about natural gas from hydraulic fracturing - fracking - it has the same emissions as regular natural gas. But it is a lot lower than coal and does not have the political baggage of nuclear energy and that is why environmentalists lobbied for it over the last 40 years.
Leguminous plants are able to grow well in infertile land, and bear many beans that are important to humans. The reason for this is because most legumes have a symbiotic relationship with bacteria, called rhizobia, that can fix nitrogen in the air and then supply the host plant with ammonia as a nutrient.
The plants create symbiotic organs called nodules in their roots. However, if too many root nodules are made it will adversely affect the growth of the plants, because the energy cost of maintaining excessive nodules is too large. Therefore legumes must have a mechanism to maintain the proper number of root nodules, but this system has been poorly understood.
Japanese researchers showed monkeys a number of images representing various glosses and then they measured the responses of 39 neurons by using microelectrodes. They found that a specific population of neurons changed the intensities of the responses linearly according to either the contrast-of-highlight, sharpness-of-highlight, or brightness of the object. This shows that these 3 perceptual parameters are used as parameters when the brain recognizes a variety of glosses. They also found that different parameters are represented by different populations of neurons. This was published in the Journal of Neuroscience (September 4, 2014 issue).
An ultrasensitive biosensor made from the wonder material graphene has been used to detect molecules that indicate an increased risk of developing cancer.
The biosensor has been shown to be more than five times more sensitive than bioassay tests currently in use, and was able to provide results in a matter of minutes, opening up the possibility of a rapid, point-of-care diagnostic tool for patients.
The biosensor has been presented today, 19 September, in IOP Publishing's journal 2D Materials.
