Scientists have reported that an experimental vaccine targeting one of the most common genetic drivers of pancreatic cancer, called mutant KRAS, is safe and generated a durable immune responses aimed at preventing the cancer.
In biology, anticipation is the term for genetic diseases caused by an abnormal repeat in DNA that becomes more severe with each new generation. Now there is a twist. A study has found the existence of anticipation in diseases caused by different errors - not a DNA repeat - in fatal neurodegenerative disorder Familial Amyloid Polyneuropathy (FAP).
The bacterium Bacillus subtilis is quite adaptable, it moves about in liquids and on agar surfaces by means of flagella and alternatively, it can just stick to an underlying substrate. The bacteria proliferate most effectively in this stationary state, while motile bacteria reproduce at a noticably lower rate. In order to sustain and extend the colony, bacteria primarily require sufficient nutrients. Moving slowly means that nutrients are soon used up, but adventurous bacteria that decide to move out fast in search for a microbial Cockaigne may end up feeling lonely. Which strategy offers the best prospects for the organisms? Should one specialize in growth or migration, or be a generalist and steer a balanced course?
A long-term study of a cohort of young people, 12,000 people now six years old, from Iceland to Greece, who have been tracked from birth and whose diets and allergies have been recorded, is evaluating maternal diet’s impact on food allergy in later life is expected to uncover causes of allergy in children.Some pointers are already evident, they note. Compared to the UK, Israeli children typically eat nuts at an earlier age and have fewer allergies, which suggests that such dietary habits may have a protective effect against nut allergies later on. “This means that the current advice that young children should avoid nuts may make things worse,” says Clare Mills, professor of allergy in the Institute of Inflammation and Repair at the University of Manchester.
Two Simon Fraser University psychologists have made a brain-related discovery that could revolutionize doctors' perception and treatment of attention-deficit disorders.
This discovery opens up the possibility that environmental and/or genetic factors may hinder or suppress a specific brain activity that the researchers have identified as helping us prevent distraction.
The Journal of Neuroscience has just published a paper about the discovery by John McDonald, an associate professor of psychology and his doctoral student John Gaspar, who made the discovery during his master's thesis research.
San Diego, Calif. (April 18, 2014) ― A new study in the American Journal of Preventive Medicine analyzing weekly patterns in health-related Google searches reveals a recurring pattern that could be leveraged to improve public health strategies.
Investigators from San Diego State University, the Santa Fe Institute, Johns Hopkins University, and the Monday Campaigns, analyzed "healthy" Google searches (searches that included the term healthy and were indeed health-related, e.g., "healthy diet") originating in the U.S. from 2005 to 2012. They found that on average, searches for health topics were 30 percent more frequent at the beginning of the week than on days later in the week, with the lowest average number of searches on Saturday.
PROVIDENCE, R.I. [Brown University] — Asteroid and comet impacts can cause widespread ecological havoc, killing off plants and animals on regional or even global scales. But new research from Brown University shows that impacts can also preserve the signatures of ancient life at the time of an impact.
A research team led by Brown geologist Pete Schultz has found fragments of leaves and preserved organic compounds lodged inside glass created by a several ancient impacts in Argentina. The material could provide a snapshot of environmental conditions at the time of those impacts. The find also suggests that impact glasses could be a good place to look for signs of ancient life on Mars.
The work is published in the latest issue of Geology Magazine.
Myelin, the electrical insulating material long believed to be essential for the fast transmission of impulses along the axons of nerve cells, is not as ubiquitous as thought, according to a new paper that turns 160 years of neuroscience on its head.
During the 20 year span of global warming policy debates, climate scientists have used an estimate of soil organic carbon sequestration rates suggesting that soil organic carbon can be sequestered by simply switching from moldboard or conventional tillage systems to no-till systems.
Optics researchers from the University of Central Florida's College of Optics&Photonics and the University of Arizona are working on a new technique to aim a high-energy laser beam into clouds to make it rain or trigger lightning. They are developing the a technique to surround a primary beam with a second beam that acts as an energy reservoir, sustaining the central beam to greater distances than previously possible.
The secondary "dress" beam refuels and helps prevent the dissipation of the high-intensity primary beam, which on its own would break down quickly.
A new article reports that listening to religious music is associated with a decrease in anxiety about death and increases in life satisfaction, self-esteem, and sense of control over their lives among older Christians.
The associations are similar for blacks and whites, women and men, and individuals of both low- and high-socioeconomic status.
Emergency contraceptive pills haven't reduced teen pregnancies or abortions but at least in America those incidents have not risen - in South America, unprotected sex is really taking a pregnancy gamble, even if there is access to a morning after pill.
A survey of emergency contraceptive pills in Peru found that 28 percent of the batches studied were either of substandard quality or falsified. Many released the active ingredient too slowly, others had the wrong active ingredient, one batch was basically homeopathy contraception - the researchers couldn't find an active ingredient at all.
The sun emitted a mid-level solar flare, peaking at 9:03 a.m. EDT on April 18, 2014, and NASA's Solar Dynamics Observatory captured images of the event. Solar flares are powerful bursts of radiation. Harmful radiation from a flare cannot pass through Earth's atmosphere to physically affect humans on the ground, however -- when intense enough -- they can disturb the atmosphere in the layer where GPS and communications signals travel.
To see how this event may impact Earth, please visit NOAA's Space Weather Prediction Center at http://spaceweather.gov, the U.S. government's official source for space weather forecasts, alerts, watches and warnings.
