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Melville on Science vs. Creation Myth

From Melville's under-appreciated Mardi: On a quest for his missing love Yillah, an AWOL sailor...

Non-coding DNA Function... Surprising?

The existence of functional, non-protein-coding DNA is all too frequently portrayed as a great...

Yep, This Should Get You Fired

An Ohio 8th-grade creationist science teacher with a habit of branding crosses on his students'...

No, There Are No Alien Bar Codes In Our Genomes

Even for a physicist, this is bad: Larry Moran, in preparation for the appropriate dose of ridicule...

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Welcome to Adaptive Complexity, where I write about genomics, systems biology, evolution, and the connection between science and literature, government, and society.

I'm a biochemist

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Show Me The Science Month Day 14

Another abstract will have to do for today's extremely delayed installment; the grant proposal leaves my desk tomorrow, so I hope to be back in business as soon as my neck recovers from days of hunching over the laptop.

Today's paper, Sequencing human–gibbon breakpoints of synteny reveals mosaic new insertions at rearrangement sites, is not just interesting because two of the senior authors work one floor below my lab, or because the other senior authors is speaking to our department on Thursday. This paper is an interesting glimpse into the chromosome shuffling that went on in our evolutionary history:
Show Me The Science Month Day 13

The grant writing has reached a fever pitch as the deadline closes in. Tomorrow 30 Days of Evolution Blogging will get back on track, but for today, a title and abstract will have to do. Today's paper is a DNA comparison study of the class of birds known as white-eyes (the Zosteropidae), which have demonstrated an amazing capacity for evolutionary diversification.


Zosterops japonicus, Courtesy the Wikipedia Commons


Explosive Pleistocene diversification and hemispheric expansion of a “great speciator”
Show Me The Science Month Day 12

Natural selection is often much like Goldilocks - an organism's traits shouldn't be too hot or too cold; natural selection likes them just right. In other words, traits are under pressure to remain near an optimum. If they deviate too far, natural selection will not-so-gently prod things back to the center. This phenomenon is known as stabilizing selection.

Stabilizing selection has to push against another powerful evolutionary force - random drift. Much of our genetic makeup is influenced by non-adaptive processes, that is, processes that are not particularly favored or disfavored by natural selection, and which do not perform some function that improves the fitness of the organism. Selection and drift have been especially hard to tease apart when it comes to gene regulation. Related species regulate their genes in different ways, but how many of those differences are simply due to random divergence? Trevor Bedford and Daniel Hartl at Harvard University take a crack at this question in a recent paper. They use a mathematical model based on Brownian motion (the kind of random motion you see when you watch pollen grains buffeted about in a drop of water) to determine how well stabilizing selection counteracts the battering of random drift.
Show Me The Science Month Day 11

Imagine a world where the major source of human nutrition was beer. That may sound fantastic to some of you, but now imagine that, in this beer-world, there are no bottle openers and no twist-off caps. To get at the beer, you have to open the bottles with your teeth. Day in, day out, you're opening bottles with your teeth. If the world continued like this for a few thousand generations, how would the human jaw evolve into a better beer bottle opener?

2 million years ago, our ancestors lived in such a world. OK, so it didn't involve beer-bottles, but our ancestors did have to use their teeth to get at what was essentially armored but highly nutritious food - nuts and seeds.
Show Me The Science Month Day 10

A pressing grant deadline is going to keep today's evolution blog entry short, but the find is no less spectacular than yesterday's fetal proto-whale fossil. A group of researchers has discovered the fossil vertebra of the largest snake known to date. At an estimated 13 meters (about 42.6 feet) long, this monster, named appropriately Titanoboa, lived in tropical South America about 60 million years ago.