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Melville on Science vs. Creation Myth

From Melville's under-appreciated Mardi: On a quest for his missing love Yillah, an AWOL sailor...

Non-coding DNA Function... Surprising?

The existence of functional, non-protein-coding DNA is all too frequently portrayed as a great...

Yep, This Should Get You Fired

An Ohio 8th-grade creationist science teacher with a habit of branding crosses on his students'...

No, There Are No Alien Bar Codes In Our Genomes

Even for a physicist, this is bad: Larry Moran, in preparation for the appropriate dose of ridicule...

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Michael WhiteRSS Feed of this column.

Welcome to Adaptive Complexity, where I write about genomics, systems biology, evolution, and the connection between science and literature, government, and society.

I'm a biochemist

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Wouldn't it be great to know if your three-year-old has the potential to be a soccer star or a top marathon runner? One genetic testing company is offering to tell you just that, so that all of you obsessive, controlling parents can get your toddlers in the proper training program right from the start.

I'm sure most of you are probably cringing at the thought of using genetics to decide what sort of future you're going to push your kid into before she can even brush her own teeth. But even if you are a parent who sees nothing wrong using a little prior information to get a head start on your kid's bright athletic career, DON'T DO IT! Leaving ethical arguments aside, there are good reasons to stay away from these tests: they are not good predictors of athletic performance.
Cancer cells of all types have one thing in common: they have escaped the built-in controls of cell reproduction, and as a result, tumors grow as the out-of-control cells keep dividing.

This out-of-control cell division in cancer is very closely connected to a process called differentiation, the process by which a cell stops dividing and transforms itself from a stem cell into a specialized cell like a red blood cell. There is a trade-off: differentiated cells are specialized and tend to not divide; undifferentiated cells tend to divide but don't carry out specialized functions. The problem with cancer cells is that they are more like undifferentiated, dividing stem cells than the non-dividing, differentiated cells we want them to be.
OK, this isn't strictly science, but take this U.S. civics quiz and then see if you do better than your average US government official.

Is it really surprising that government officials did worse than the average in this survey?

I got 31 out of 33 - how did you all do?

Yesterday our department hosted Peter and Rosemary Grant, who spoke about their 30+ years studying natural selection and finches in the Galapagos. (If you're interested in the book version of their work, check out Jonathan Weiner's Pulitzer Prize-winning The Beak of the Finch.)

While the Grants give a great presentation, full of pictures the Galapagos finches in action, my first impression was that none of this was really groundbreaking. As the Grants mentioned multiple times in the talk, Darwin anticipated so much of what they observe in the Galapagos. In an age of molecular genetics, a long-term, non-molecular field study is bound to seem a little old fashioned, although the Grants have recently been taking DNA samples and incorporating the tools of molecular genetics into their work.

In the end, I came away from the talk satisfied. This work may not be conceptually groundbreaking, but I find it important for at least one reason: this is evolution in detail, in the wild.
...at Redneck Genetics. It's now Dr. Redneck Geneticist. Justin successfully finished his PhD this week - head on over and congratulate him, now that he's sober again.


Oppenheimer: The Tragic Intellect


Charles Thorpe, University of Chicago 2006

For decades, there was a dearth of comprehensive Oppenheimer biographies. As Thomas Powers noted in the New York Review of Books, biographies of other major Manhattan Project figures came out long before adequate Oppenheimer biographies: "Oppenheimer, the truly central figure, seemed to resist the attempt to write his life on the grand scale." That is no longer the case, and a shelf of very good biographies makes it difficult to know where to start reading.