Why Both Stimulating And Blocking GLP-1R Helps People Lose Weight
Understanding which brain circuits respond to weight loss medications and how they behave could lead to better weight loss with fewer side effects.
Understanding which brain circuits respond to weight loss medications and how they behave could lead to better weight loss with fewer side effects.
A study today highlighted a new therapeutic technique to repair and rebuild muscle for sufferers of degenerative muscle disorders. The therapy brings together two existing techniques for muscle repair, cell transplantation and tissue engineering - mesoangioblast stem cells delivered via a hydrogel cell-carrier matrix.
Some people take risks with investments while others on safety with their money and in other business activities. Researchers have looked at the attitudes towards risk in a group of 56 subjects and found that in people who preferred safety, certain regions of the brain show a higher level of activation when they are confronted with quite unforeseeable situations.
Marketing people follow predictable patterns; in order to sell something it either needs to scare people or make them feel good. "This ain't your father's" X is a timeless perceptual classic, meaning it is not old-fashioned and conservative and boring like parents.
Clostridium acetobutylicum became popular when the chemist Chaim Weizmann first used the bacterium to ferment the solvent acetone and the alcohols butanol and ethanol, collectively known as “ABE” products, from starch - he wanted to create synthetic rubber and during World War I the process was used by the British to ferment acetone for the production of cordite, the explosive propellant that replaced gunpowder in bullets and artillery shells.
Mountain glaciers respond to climate change by rapidly advancing or receding as global temperatures have spiked upward and downward numerous times throughout geological history. Those changes in glacier extent control hydrology, sediment transport, and deposition in rivers downstream.
The sedimentary record in glaciated catchments therefore is an important archive with that can help unravel past climate changes but, unlike rivers, whose flow is controlled entirely by land surface topography, glaciers are able to flow uphill and across ridgelines - a process called "transfluence." Glacier advance and recession can result in drainage capture by transfluent ice flow, and so change catchment drainage areas and hydrological budgets.
How some dahlias, white, yellow, red or purple, get their color is well known, but the molecular mechanism behind the black dahlia has been a mystery. A new study shows that the distinctive black-red coloring is based on an increased accumulation of anthocyanins as a result of drastically reduced concentrations of flavones.
Dahlia variabilis hort. is a popular garden flower. Continuous dahlia breeding worldwide has led to the availability of a huge number of cultivars, 20,000 varieties, many of them showing red hues. However, black hues of dahlia flowers occur rarely, in comparison.
Some people have a distinct, disabling sleep disorder called "primary hypersomnia" - they regularly sleep more than 70 hours per week and have difficulties awakening.
Even when awake, they still have reaction times comparable to someone who has been awake all night. Their sleepiness often interferes with work or school attendance, and conventional treatments such as stimulants bring little relief.
A universal approach to helping people who witnessed or experience genocide may be misguided, says an anthropologist.
The experience of genocide as transmitted trauma may not be universal but in the fields of human rights and memory studies, giving testimony about one's personal experience of genocide is believed to be both a moral duty and a psychological imperative for the wellbeing of the individual and the persecuted group to which they belong. The coping strategies for victims of genocide tend to be uniform: tell your story and do not let the violence you suffered be forgotten. What about descendants?
Bones are resilient and heal well after most fractures but in cases of traumatic injury, where large pieces of bone are missing, healing is much more difficult and sometimes impossible.
"Large segmental defects" are a major clinical problem, especially among the military in places like Afghanistan, and orthopedic surgeons struggle to treat them but new research results confirm that the bone healing process of large segmental defects is sensitive to its mechanical environment and suggests that "reverse dynamization," a straightforward and inexpensive process, could help speed healing of these traumatic injuries.
Studying the genetic variability of endangered species will be necessary for species conservation and monitoring but endangered species are difficult to observe and sample and typically have very limited genetic diversity.
A research team has taken advantage of DNA sequencing methodology developed by Floragenex to identify the genetic markers for the Bornean elephant, an endangered species, using blood from very few animals. The results showed that Bornean elephants have very low genetic variability that can impact on their survival to a threatened habitat, but that variable genetic markers can still be identified. The study opens new avenues for the conservation of other endangered species.
An enzyme used in nature can make powerful chemicals as diverse as catnip and a cancer drug, vinblastine, which opens up the prospect of producing these chemicals cheaply and efficiently.
A new class of materials has shown to be able to form dynamic, moving structures.
Researchers have demonstrated tiny spheres that synchronize their movements as they self-assemble into a spinning microtube. The researchers used tiny particles called Janus spheres, named after the Roman god with two faces, which have been previously demonstrated for self-assembly of static structures. In this study, one half of each sphere is coated with a magnetic metal. When dispersed in solution and exposed to a rotating magnetic field, each sphere spins in a gyroscopic motion. They spin at the same frequency but all face a different direction, like a group of dancers in a ballroom dancing to the same beat but performing their own steps.